感染類疾病

感染類疾病是由細菌、病毒、真菌和寄生蟲等不同病原體引起的疾病，能夠影響人體各個系統和器官。這些疾病可以表現為輕微的皮膚感染，也可以是嚴重的全身性感染，如敗血癥。常見的感染類疾病包括細菌性肺炎、尿路感染、結核病；病毒性感染如流感、艾滋病、登革熱、COVID-19；真菌性感染如念珠菌病、癬病；以及寄生蟲感染如瘧疾、弓形蟲病。

治療感染類疾病通常需要使用相應的抗生素、抗病毒藥、抗真菌藥或抗寄生蟲藥，而疫苗接種是預防某些感染性疾病的有效手段。面對耐藥性微生物的挑戰，新藥的研發和現有藥物的改進對于治療和控制感染類疾病至關重要。

在藥物研發方面，進展如下：

抗菌藥物：研究集中在開發新型抗生素以對抗耐藥性問題，探索新的分子實體和作用機制，包括β內酰胺類、大環內酯類、喹諾酮類和碳青霉烯類抗生素的新型變體。
抗病毒藥物：研發進展包括針對病毒復制酶、病毒蛋白酶、病毒進入宿主細胞的抑制，以及病毒釋放的阻斷，如流感的奧司他韋和HIV的逆轉錄酶及蛋白酶抑制劑。
抗真菌藥物：研發重點在于解決耐藥性問題，開發新藥以干擾真菌細胞壁合成、影響真菌膜完整性和抑制真菌DNA復制，如棘白菌素類和嘧啶類似物。
抗寄生蟲藥物：治療研究致力于干擾寄生蟲的代謝途徑、細胞結構，以及改變宿主-寄生蟲的相互作用。
免疫調節劑和生物制劑：旨在增強宿主的免疫反應或減少自身免疫反應和炎癥，包括干擾素、腫瘤壞死因子(TNF)抑制劑和其他生物制劑。
疫苗：疫苗研發是預防感染性疾病的關鍵，包括新型疫苗設計，如針對COVID-19的mRNA疫苗和病毒載體疫苗，以及現有疫苗的改進。

感染類疾病藥物靶點

感染類疾病靶點相關產品推薦

● 靶點蛋白

MS4A1 (CD20)
CSB-MP015007HU

Measured by its binding ability in a functional ELISA. Immobilized human CD20 at 2 μg/ml can bind Anti-CD20 recombinant antibody (CSB-RA015007A1HU), the EC₅₀ is 3.243-7.085 ng/mL

TNFRSF17
CSB-MP023974HU1

Human TNFSF13B protein Fc tag (CSB-MP897523HU1) captured on COOH chip can bind Human BCMA protein Fc tag (CSB-MP023974HU1) with an affinity constant of 39 nM as detected by LSPR Assay.

PDCD1
CSB-MP619964HU1

Measured by its binding ability in a functional ELISA. Immobilized PD-1 at 2 μg/ml can bind Anti-PD-1 recombinant antibody, the EC₅₀ of human PD-1 protein is 6.087-7.854 ng/ml.

CD22
CSB-MP004900HU

Measured by its binding ability in a functional ELISA. Immobilized CD22 at 2 μg/ml can bind Anti-CD22 rabbit monoclonal antibody, the EC₅₀ of human CD22 protein is 4.034-4.800 ng/ml.

CD274
CSB-MP878942HU1

Measured by its binding ability in a functional ELISA. Immobilized PD-L1 at 2 μg/ml can bind Anti- PD-L1 mouse monoclonal antibody (CSB-MA878942A1m, antigen from E.coli), the EC₅₀ of human PD-L1 protein is 1.252-1.653 ng/mL

CD47
CSB-MP004940HU

Human SIRPA protein His/Myc tag (CSB-MP021334HU) captured on COOH chip can bind Human CD47 protein Fc tag (CSB-MP004940HU) with an affinity constant of 19.1 nM as detected by LSPR Assay.

TNFRSF8
CSB-MP023983HU1

Measured by its binding ability in a functional ELISA. Immobilized CD30 at 5 μg/ml can bind human CD30L (CSB-MP023996HU1c9), the EC₅₀ is 14.96-20.25 ng/ml

IL2RA
CSB-MP011649HU3

Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU)，the EC₅₀ is 2.463-3.353 ng/mL.

產品名稱	貨號	靶點	來源	蛋白標簽
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial (Active)	CSB-AP005671HU	ACE2	Mammalian cell	C-terminal 6xHis-tagged
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial, Biotinylated (Active)	CSB-MP866317HU-B	ACE2	Mammalian cell	C-terminal mFc-Avi-tagged
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial (Active)	CSB-MP866317HU	ACE2	Mammalian cell	C-terminal hFc-tagged
Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active)	CSB-MP3414MOV	ACE2	Mammalian cell	C-terminal hFc-tagged
Recombinant Paguma larvata Angiotensin-converting enzyme 2 (ACE2), partial (Active)	CSB-MP684964PAL	ACE2	Mammalian cell	C-terminal hFc-tagged
Recombinant Human Basigin (BSG), partial (Active)	CSB-MP002831HU1	BSG	Mammalian cell	C-terminal hFc-tagged
Recombinant Human B-lymphocyte antigen CD19 (CD19), partial (Active)	CSB-AP005061HU	CD19	Mammalian cell	C-terminal Fc-tagged
Recombinant Human B-cell receptor CD22 (CD22), partial (Active)	CSB-MP004900HU	CD22	Mammalian cell	C-terminal 6xHis-tagged
Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial (Active)	CSB-MP878942HU1	CD274	Mammalian cell	C-terminal hFc-tagged
Recombinant Human Myeloid cell surface antigen CD33 (CD33), partial (Active)	CSB-MP004925HU	CD33	Mammalian cell	C-terminal hFc-Myc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active)	CSB-AP005181HU	CD40	Mammalian cell	C-terminal Fc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active)	CSB-MP004936HU1	CD40	Mammalian cell	C-terminal hFc-tagged
Recombinant Human CD40 ligand (CD40LG), partial (Active)	CSB-AP005191HU	CD40LG	E.coli	Tag-Free
Recombinant Human CD40 ligand (CD40LG), partial (Active)	CSB-MP004937HU3	CD40LG	Mammalian cell	N-terminal hFc-Flag-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active)	CSB-AP005201HU	CD47	Mammalian cell	C-terminal 6xHis-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active)	CSB-AP005211HU	CD47	Mammalian cell	C-terminal Fc-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active)	CSB-MP004940HU	CD47	Mammalian cell	C-terminal hFc-tagged
Recombinant Human T-cell antigen CD7 (CD7), partial (Active)	CSB-MP004953HU	CD7	Mammalian cell	C-terminal hFc-Myc-tagged
Recombinant Human CD70 antigen (CD70), partial (Active)	CSB-MP004954HU1	CD70	Mammalian cell	N-terminal 10xHis-tagged
Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial (Active)	CSB-AP005161HU	CD86	Mammalian cell	C-terminal 6xHis-tagged

● 穩定細胞株

CT26/Human ROR1 Stable Cell Line

CSB-SC020067HU

Untransfected CT26 cells (green line) and transfected Human ROR1 CT26 stable cells (red line) were stained with anti-ROR1 antibody (CSB-RA020067A1HU) (2μg/1*10⁶ cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

● 重組抗體

CD247 Recombinant Monoclonal Antibody
CSB-RA244537A0HU

Overlay Peak curve showing Jurkat cells surface stained with CSB-RA244537A0HU (red line) at 1:50.

CD274 Recombinant Monoclonal Antibody
CSB-RA878942MA1HU

Overlay Peak curve showing Hela cells surface stained with CSB-RA878942MA1HU (red line) at 1:100.

CD40 Recombinant Monoclonal Antibody
CSB-RA004936MA1HU

Overlay Peak curve showing THP-1 cells surface stained with CSB-RA004936MA1HU (red line) at 1:100.

EGFR Recombinant Monoclonal Antibody
CSB-RA159341A0HU

Overlay histogram showing Jurkat cells stained with CSB-RA159341A0HU (red line) at 1:50.

產品名稱	貨號	靶點	反應種屬	應用范圍
ALB Recombinant Monoclonal Antibody	CSB-RA264109A0HU	ALB	Human	ELISA, FC
CD19 Recombinant Monoclonal Antibody	CSB-RA004888A0HU	CD19	Human	ELISA
CD19 Recombinant Monoclonal Antibody	CSB-RA780821A0HU	CD19	Human	ELISA, WB, IHC, IP
CD19 Recombinant Monoclonal Antibody	CSB-RA004888MA1HU	CD19	Human, Mouse	ELISA, WB
CD22 Recombinant Monoclonal Antibody	CSB-RA962691A0HU	CD22	Human	ELISA, IHC
CD247 Recombinant Monoclonal Antibody	CSB-RA244537A0HU	CD247	Human	ELISA, FC
CD274 Recombinant Monoclonal Antibody	CSB-RA977797A0HU	CD274	Human	ELISA, WB, IHC
CD274 Recombinant Monoclonal Antibody	CSB-RA878942MA1HU	CD274	Human	ELISA, IHC, FC
CD38 Recombinant Monoclonal Antibody	CSB-RA796695A0HU	CD38	Human	ELISA, WB, IHC
CD3E Recombinant Monoclonal Antibody	CSB-RA004931MA1HU	CD3E	Human	ELISA, FC
CD4 Recombinant Monoclonal Antibody	CSB-RA004935A0HU	CD4	Human	ELISA, WB, IHC
CD40 Recombinant Monoclonal Antibody	CSB-RA004936MA1HU	CD40	Human	ELISA, IF, FC
CD47 Recombinant Monoclonal Antibody	CSB-RA802124A0HU	CD47	Human	ELISA, WB, IHC, IF
CD70 Recombinant Monoclonal Antibody	CSB-RA004954MA1HU	CD70	Human	ELISA
CD80 Recombinant Monoclonal Antibody	CSB-RA246383A0HU	CD80	Human	ELISA, WB, IHC, IP
CD86 Recombinant Monoclonal Antibody	CSB-RA004965A0HU	CD86	Human	ELISA, WB
CTLA4 Recombinant Monoclonal Antibody	CSB-RA213310A0HU	CTLA4	Human	ELISA, IHC
CTLA4 Recombinant Monoclonal Antibody	CSB-RA006163MA1HU	CTLA4	Human, Mouse	ELISA, WB, IF, FC
CXCL10 Recombinant Monoclonal Antibody	CSB-RA903061A0HU	CXCL10	Human	ELISA, IHC
CXCR4 Recombinant Monoclonal Antibody	CSB-RA569311A0HU	CXCR4	Human	ELISA, IF

● ELISA試劑盒

產品名稱	貨號	靶點	檢測范圍	靈敏度
Rat Angiotensin converting enzyme 2, ACE2 ELISA Kit	CSB-E14308r	ACE2	0.02 ng/ml - 20 ng/ml	0.02 ng/ml
Human Angiotensin converting enzyme 2, ACE2 ELISA Kit	CSB-E04489h	ACE2	0.156 ng/mL-10 ng/mL	0.039 ng/mL
Mouse Angiotensin converting enzyme 2(ACE2)ELISA Kit	CSB-E17204m	ACE2	6.25 pg/mL-400 pg/mL	1.56 pg/mL
Bovine Albumin(Alb) ELISA kit	CSB-E08664b	ALB	0.313 μg/mL-80 μg/mL	0.148 μg/mL
Mouse Albumin (Alb)ELISA Kit	CSB-E13878m	ALB	0.781 μg/mL-200 μg/mL	0.110 μg/mL
Dog Albumin(Alb) ELISA Kit	CSB-E15757c	ALB	0.273 μg/mL-35 μg/mL	0.266 μg/mL
Sheep Albumin (Alb)ELISA Kit	CSB-E15839Sh	ALB	350 μg/mL-21.88 μg/mL	5.5 μg/mL
Horse Albumin(Alb) ELISA Kit	CSB-E16205Hs	ALB	1.25 μg/mL-80 μg/mL	1.247 μg/mL
Pig Albumin (Alb) ELISA Kit	CSB-E16207p	ALB	0.03 μg/mL-7000 μg/mL	0.03 μg/mL
Goat Albumin (Alb)ELISA Kit	CSB-E15758G	ALB	0.17 μg/mL-350 μg/mL	0.17 μg/mL
Guinea Pig Albumin(Alb) ELISA kit	CSB-E15765Gp	ALB	0.156 μg/mL-10 μg/mL	0.09 μg/mL
Rabbit Albumin(Alb) ELISA Kit	CSB-E16204Rb	ALB	0.273 μg/mL-70 μg/mL	0.117 μg/mL
Human Cluster of differentiation 147,CD147 Elisa Kit	CSB-E12994h	BSG	12.5 pg/mL-800 pg/mL	3.12 pg/mL
Human soluble cluster of differentiation 14,sCD14 ELISA Kit	CSB-E13199h	CD14	0.234 ng/mL-15 ng/mL	0.229 ng/mL
Rat soluble cluster of differentiation 14,sCD14 ELISA Kit	CSB-E11178r	CD14	28 ng/mL-1800 ng/mL	7 ng/mL
Human T-cell surface glycoprotein CD3 zeta chain (CD247) ELISA kit	CSB-EL004904HU	CD247	0.156 ng/mL-10 ng/mL	0.039 ng/mL
Human Programmed Death Ligand-1(PD-L1/CD274) ELISA Kit	CSB-E13644h	CD274	15.6 pg/mL-1000 pg/mL	3.9 pg/mL
Mouse Programmed cell death 1 ligand 1(CD274) ELISA kit	CSB-EL004911MO	CD274	31.25 pg/mL-2000 pg/mL	7.81 pg/mL
Human soluble cluster of differentiation 28,sCD28 ELISA Kit	CSB-E09296h	CD28	0.625 ng/mL-40 ng/mL	0.156 ng/mL
Human Myeloid cell surface antigen CD33(CD33) ELISA kit	CSB-EL004925HU	CD33	125 pg/mL-8000 pg/mL	31.25 pg/mL