CD52
CD52，即分化簇52，別名Campath-1、HE5。它是由CD52基因編碼的糖蛋白，廣泛表達(dá)于免疫細(xì)胞的細(xì)胞表面，例如成熟的淋巴細(xì)胞、天然殺傷細(xì)胞（NK）、嗜酸性粒細(xì)胞、嗜中性粒細(xì)胞、單核細(xì)胞/巨噬細(xì)胞和樹突狀細(xì)胞（DC）。CD52是一個(gè)錨定在糖基磷脂酰肌醇（GPI）上的12個(gè)氨基酸的糖蛋白，其功能可能與抗粘連有關(guān)，允許細(xì)胞自由移動(dòng)。在作用機(jī)制上，CD52通過其細(xì)胞表面分子的連接可為T細(xì)胞活化和增殖提供共刺激信號(hào)，同時(shí)，可溶性CD52分子與抑制唾液酸結(jié)合的免疫球蛋白樣凝集素10（Siglec-10）相互作用，從而顯著抑制T細(xì)胞的增殖和活化。CD52在調(diào)節(jié)免疫反應(yīng)中起著重要作用，尤其是在T細(xì)胞的激活和自身免疫性疾病的發(fā)展中。
熱銷產(chǎn)品
Recombinant Human CAMPATH-1 antigen (CD52), partial (CSB-MP004943HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded Human-spleen, antibody was diluted at 1:100
Human CAMPATH-1 antigen(CD52) ELISA kit (CSB-EL004943HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL004943HU
規(guī)格：96T/48T
靈敏度：19.5 ng/mL
檢測(cè)范圍：78 ng/mL-5000 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CD52 Antibodies
CD52 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA338154 | CD52 Antibody | Human | IHC,ELISA |
CD52 Proteins
CD52 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004943HU | Recombinant Human CAMPATH-1 antigen (CD52), partial | Yeast |
| CSB-EP004943HU | Recombinant Human CAMPATH-1 antigen (CD52) | E.coli |
| CSB-BP004943HU CSB-EP004943HU-B |
Recombinant Human CAMPATH-1 antigen (CD52), partial | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP004943HU | Recombinant Human CAMPATH-1 antigen (CD52), partial | Mammalian cell |
CD52 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004943MOV CSB-EP004943MOV CSB-BP004943MOV CSB-MP004943MOV CSB-EP004943MOV-B |
Recombinant Macaca fascicularis CAMPATH-1 antigen (CD52) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD52 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP638949DO CSB-EP638949DO CSB-BP638949DO CSB-MP638949DO CSB-EP638949DO-B |
Recombinant Dog CAMPATH-1 antigen (CD52) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD52 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP720668MO CSB-EP720668MO CSB-BP720668MO CSB-MP720668MO CSB-EP720668MO-B |
Recombinant Mouse CAMPATH-1 antigen (Cd52) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD52 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733908RA CSB-EP733908RA CSB-BP733908RA CSB-MP733908RA CSB-EP733908RA-B |
Recombinant Rat CAMPATH-1 antigen (Cd52) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD52 ELISA Kit
CD52 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL004943HU | Human CAMPATH-1 antigen(CD52) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 19.5 ng/mL |
