IL22RA1
IL22RA1，即白介素22受體α1，別名IL-22Rα1、CRF2-9等。它是一種由IL22RA1基因編碼的蛋白質(zhì)，是IL-22受體的α亞基，與IL-10Rβ鏈共用形成IL-22的高親和力受體。IL22RA1的作用機(jī)制涉及與IL-22結(jié)合后，激活JAK/STAT信號通路，從而抑制IL-22介導(dǎo)的細(xì)胞增殖和抗凋亡。IL22RA1主要分布于胰、肝、小腸、結(jié)腸、腎等組織，參與調(diào)節(jié)上皮細(xì)胞的遷移能力、肝細(xì)胞的保護(hù)作用、呼吸道和胃腸道細(xì)胞的修復(fù)以及組織修復(fù)作用。此外，IL22RA1還參與了細(xì)菌防御、炎癥性疾病的發(fā)生發(fā)展等過程，是相關(guān)疾病研究和治療的潛在靶點。
熱銷產(chǎn)品
Recombinant Human Interleukin-22 receptor subunit alpha-1 (IL22RA1), partial (CSB-EP822717HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IL22RA1 Antibody (CSB-PA822717ESR2HU)
驗證數(shù)據(jù)
Western blot
All lanes: IL22RA1 antibody at 10μg/ml
Lane 1: Mouse spleen tissue
Lane 2: HepG2 whole cell lysate
Lane 3: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63 kDa
Observed band size: 63 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA822717ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA822717ESR2HU at dilution of 1:100
IL22RA1 Antibodies
IL22RA1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011636GA01HU | IL22RA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA822717LA01HU | IL22RA1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA822717LC01HU | IL22RA1 Antibody, FITC conjugated | Human | |
| CSB-PA822717ESR2HU | IL22RA1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA279247 | IL22RA1 Antibody | Human | ELISA,IHC |
| CSB-PA903370 | IL22RA1 Antibody | Human | ELISA,IHC |
IL22RA1 Proteins
IL22RA1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP666170BO CSB-EP666170BO CSB-BP666170BO CSB-MP666170BO CSB-EP666170BO-B |
Recombinant Bovine Interleukin-22 receptor subunit alpha-1 (IL22RA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL22RA1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP802252MO CSB-EP802252MO CSB-BP802252MO CSB-MP802252MO CSB-EP802252MO-B |
Recombinant Mouse Interleukin-22 receptor subunit alpha-1 (Il22ra1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL22RA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP822717HU CSB-BP822717HU CSB-MP822717HU CSB-EP822717HU-B |
Recombinant Human Interleukin-22 receptor subunit alpha-1 (IL22RA1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP822717HU | Recombinant Human Interleukin-22 receptor subunit alpha-1 (IL22RA1), partial | E.coli |
