IL5
IL5，即白介素5，它主要由活化的T細胞產(chǎn)生，也可由某些人T細胞白血病細胞系、EB病毒轉(zhuǎn)化的B細胞以及嗜酸性粒細胞產(chǎn)生。IL5的作用機制涉及到與特定的細胞表面受體結(jié)合，其受體由IL-5Rα鏈和信號傳導(dǎo)亞基βc組成，形成高親和受體。IL5通過與IL-5Rα的低親和結(jié)合，再緊密結(jié)合βc二聚體，激活下游的信號傳導(dǎo)途徑，如JAK/STAT通路，進而促進嗜酸性粒細胞的分化、成熟、活化、遷移和存活。IL5在生物學(xué)上的意義主要體現(xiàn)在其對嗜酸性粒細胞相關(guān)生物學(xué)過程的調(diào)控作用。它在寄生蟲感染和過敏性疾病的發(fā)病機制中起到關(guān)鍵作用，特別是在嗜酸性粒細胞增多癥和某些變態(tài)反應(yīng)性疾病中，IL5的水平會增高。IL5通過促進嗜酸性粒細胞的增殖和活化，增強其殺傷腫瘤細胞和病原體的能力，同時在粘膜免疫中也發(fā)揮重要作用。此外，IL5還參與調(diào)節(jié)B細胞的分化和抗體的產(chǎn)生，尤其是在IgA的合成中具有協(xié)同作用。因此，IL5是免疫應(yīng)答中的一個重要細胞因子，對維持免疫平衡和防御機制具有重要影響。
熱銷產(chǎn)品
Recombinant Human Interleukin-5 (IL5) (CSB-MP011662HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The purity of IL5 was greater than 95% as determined by SEC-HPLC
驗證數(shù)據(jù)
Western Blot analysis of HuvEc cells using IL-5 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using CSB-PA003033 at dilution of 1:100
Rat Interleukin 5,IL-5 ELISA KIT (CSB-E07435r)
驗證數(shù)據(jù)
貨號：CSB-E07435r
規(guī)格：96T/48T
靈敏度：3.9 pg/mL
檢測范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL5 Antibodies
IL5 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA003033 | IL5 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
IL5 Proteins
IL5 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662MOW CSB-EP011662MOW CSB-BP011662MOW CSB-MP011662MOW CSB-EP011662MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003091MOW | Recombinant Rhesus Macaque Interleukin-5 protein (IL5) (Active) | E.Coli |
IL5 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662BO CSB-EP011662BO CSB-BP011662BO CSB-MP011662BO CSB-EP011662BO-B |
Recombinant Bovine Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662MO CSB-EP011662MO CSB-BP011662MO CSB-MP011662MO CSB-EP011662MO-B |
Recombinant Mouse Interleukin-5 (Il5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003311MO | Recombinant Mouse Interleukin-5 protein (Il5) | E.Coli |
IL5 Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662HO CSB-EP011662HO CSB-BP011662HO CSB-MP011662HO CSB-EP011662HO-B |
Recombinant Horse Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662GU CSB-EP011662GU CSB-BP011662GU CSB-MP011662GU CSB-EP011662GU-B |
Recombinant Guinea pig Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662CA CSB-EP011662CA CSB-BP011662CA CSB-MP011662CA CSB-EP011662CA-B |
Recombinant Cat Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011662DRI CSB-EP011662DRI CSB-BP011662DRI CSB-MP011662DRI CSB-EP011662DRI-B |
Recombinant Cercocebus atys Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP637909SH CSB-EP637909SH CSB-BP637909SH CSB-MP637909SH CSB-EP637909SH-B |
Recombinant Sheep Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733829MRA CSB-EP733829MRA CSB-BP733829MRA CSB-MP733829MRA CSB-EP733829MRA-B |
Recombinant Meriones unguiculatus Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP842539DO CSB-EP842539DO CSB-BP842539DO CSB-MP842539DO CSB-EP842539DO-B |
Recombinant Dog Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Sigmodon hispidus (Hispid cotton rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP861706SZK CSB-EP861706SZK CSB-BP861706SZK CSB-MP861706SZK CSB-EP861706SZK-B |
Recombinant Sigmodon hispidus Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP863067PI | Recombinant Pig Interleukin-5 (IL5) | Yeast |
| CSB-EP863067PI | Recombinant Pig Interleukin-5 (IL5) | E.coli |
| CSB-BP863067PI CSB-MP863067PI CSB-EP863067PI-B |
Recombinant Pig Interleukin-5 (IL5) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Macropus eugenii (Tammar wallaby)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP895944MPE CSB-EP895944MPE CSB-BP895944MPE CSB-MP895944MPE CSB-EP895944MPE-B |
Recombinant Macropus eugenii Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-AP001721HU | Recombinant Human Interleukin-5 protein (IL5) | E.Coli |
| CSB-EP011662HU CSB-BP011662HU CSB-EP011662HU-B |
Recombinant Human Interleukin-5 (IL5) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-YP011662HU | Recombinant Human Interleukin-5 (IL5) | Yeast |
| CSB-AP004291HU | Recombinant Human Interleukin-5 (IL5) (Active) | Mammalian cell |
| CSB-MP011662HU | Recombinant Human Interleukin-5 (IL5) | Mammalian cell |
| CSB-MP011662HUa0 | Recombinant Human Interleukin-5 (IL5) | Mammalian cell |
| CSB-YP011662HUa0 | Recombinant Human Interleukin-5 (IL5) | Yeast |
IL5 ELISA Kit
IL5 ELISA Kit for Guinea Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12064Gp | Guinea pig interleukin 5,IL-5 ELISA Kit | serum, plasma, tissue homogenates | 7.81 pg/mL |
IL5 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04636h | Human Interleukin 5,IL-5 ELISA KIT | serum, plasma, tissue homogenates | 0.97 pg/ml |
IL5 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04637m | Mouse Interleukin 5,IL-5 ELISA KIT | serum, plasma, tissue homogenates | 3.9 pg/ml |
IL5 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07435r | Rat Interleukin 5,IL-5 ELISA KIT | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/mL |
