INSR
INSR，即胰島素受體（Insulinreceptor），別名IGFR、IRR。INSR由人類INSR基因編碼，該基因位于19號(hào)染色體的p13.2區(qū)域。INSR是一種跨膜受體酪氨酸激酶，屬于受體酪氨酸激酶家族的Ⅱ型亞家族。當(dāng)胰島素與其受體結(jié)合后，通過一系列結(jié)構(gòu)構(gòu)象變化，激活胞內(nèi)酪氨酸激酶活性，起始胞內(nèi)信號(hào)傳導(dǎo)。
INSR在調(diào)節(jié)血糖水平中發(fā)揮關(guān)鍵作用，促進(jìn)葡萄糖進(jìn)入肝細(xì)胞、肌細(xì)胞、脂肪細(xì)胞及其他組織細(xì)胞合成糖原，降低血糖，并促進(jìn)脂肪及蛋白質(zhì)的合成。INSR的異常可能導(dǎo)致多種代謝性疾病，包括糖尿病和胰島素抵抗。
熱銷產(chǎn)品
Recombinant Human Insulin receptor (INSR),Partial (CSB-EP011753HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
INSR Antibody (CSB-PA011753LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA011753LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA011753LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA011753LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
INSR Antibodies
INSR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011753GA01HU | INSR Antibody | Human,Rat | ELISA,WB,IP |
| CSB-PA202534 | Phospho-INSR (Tyr1361) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA203919 | Phospho-INSR (Tyr1355) Antibody | Human | ELISA,WB |
| CSB-PA945193 | INSR (Ab-1375) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA994563 | Phospho-INSR (Thr1375) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA003043 | INSR Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA011224 | Phospho-INSR (T1375) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011225 | Phospho-INSR (Y1355) Antibody | Human | WB, IHC, ELISA |
| CSB-PA011226 | Phospho-INSR (Y1361) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011227 | INSR Antibody | Human,Mouse,Rat | IF, ELISA |
| CSB-PA011228 | INSR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011229 | INSR Antibody | Human | IHC, IF, ELISA |
| CSB-PA410086 | INSR Antibody | Human | IHC,ELISA |
| CSB-PA011753LA01HU | INSR Antibody | Human | ELISA, IHC, IF |
| CSB-PA011753LB01HU | INSR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011753LC01HU | INSR Antibody, FITC conjugated | Human | |
| CSB-PA011753LD01HU | INSR Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA155156A0HU | INSR Recombinant Monoclonal Antibody | Human | ELISA, IF |
INSR Proteins
INSR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011753MO1 CSB-EP011753MO1 CSB-BP011753MO1 CSB-MP011753MO1 CSB-EP011753MO1-B |
Recombinant Mouse Insulin receptor (Insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011753RA CSB-EP011753RA1 CSB-BP011753RA1 CSB-MP011753RA1 CSB-EP011753RA-B |
Recombinant Rat Insulin receptor (Insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011753HU CSB-BP011753HU CSB-EP011753HU-B |
Recombinant Human Insulin receptor (INSR), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF011753HU(A4) | Recombinant Human Insulin receptor (INSR) | in vitro E.coli expression system |
| CSB-EP011753HU | Recombinant Human Insulin receptor (INSR),Partial | E.coli |
INSR Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011753XBE CSB-EP011753XBE CSB-BP011753XBE CSB-MP011753XBE CSB-EP011753XBE-B |
Recombinant Xenopus laevis Insulin receptor (insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011753MOW CSB-EP011753MOW CSB-BP011753MOW CSB-MP011753MOW CSB-EP011753MOW-B |
Recombinant Macaca mulatta Insulin receptor (INSR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
