TNFSF15

TNFSF15，也稱為血管內皮生長抑制因子（VEGI）或TL1A，是由TNFSF15基因編碼的蛋白質，位于染色體9q32上。該蛋白質由251個氨基酸組成，包含胞質結構域、跨膜域和胞外結構域，并能形成穩定的同源三聚體結構。TNFSF15主要作為死亡受體3（DR3）的配體，參與調控VEGF/VEGFR信號通路，影響內皮細胞的增殖、凋亡以及淋巴管生成等過程。它在血管生成、淋巴管形成、免疫調節等多個方面發揮重要作用，并為涉及血管通透性增加的病理過程（如腫瘤、腦卒中等）的治療提供了新的靶點。

更多相關閱讀：TNFSF15/TL1A：藥企巨頭搶灘布局，下一個百億級靶點的崛起之路

熱銷產品

Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active) (CSB-MP023992HU1-B)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF15 at 2 μg/ml on streptavidin coated plates can bind Anti-TNFSF15 antibody (CSB-RA023992MA1HU). The EC₅₀ is 0.2732 - 0.6370 ng/mL.

Recombinant Macaca mulatta Tumor necrosis factor ligand superfamily member 15 (TNFSF15), partial, Biotinylated (Active) (CSB-MP5305MOW-B)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Anti-TNFSF15 recombinant antibody (CSB-RA023992MA1HU) at 2 μg/ml can bind Biotinylated Macaca mulatta TNFSF15. The EC₅₀ is 0.2589-0.3025 ng/mL.

TNFSF15 Recombinant Monoclonal Antibody (CSB-RA023992MA1HU)

驗證數據

The Binding Activity of Biotinylated Macaca mulatta TNFSF15 with Anti-TNFSF15 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-TNFSF15 recombinant antibody at 2 μg/mL can bind Biotinylated Macaca mulatta TNFSF15 (CSB-MP5305MOW-B). The EC₅₀ is 0.2589-0.3025 ng/mL.

The Binding Activity of Biotinylated TNFSF15 with Anti-TNFSF15 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Biotinylated Human TNFSF15 at 2 μg/mL on streptavidin coated plates can bind Anti-TNFSF15 recombinant antibody (CSB-RA023992MA1HU). The EC₅₀ is 0.2732 - 0.6370 ng/mL.

The Binding Activity of Mouse Tnfsf15 with Anti-TNFSF15 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Tnfsf15 (CSB-MP729268MO) at 2 μg/mL can bind Anti-TNFSF15 recombinant antibody. The EC₅₀ is 1.671-2.506 ng/mL.

TNFSF15 Antibody

TNFSF15 Protein

TNFSF15 ELISA Kit

TNFSF15 Antibodies

TNFSF15 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA983205	TNFSF15 Antibody	Human	ELISA,WB,IF
CSB-PA004447	TNFSF15 Antibody	Human	WB, IF, ELISA
CSB-PA577745	TNFSF15 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA065340	TNFSF15 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA023992ESR1HU	TNFSF15 Antibody	Human, Mouse	ELISA, WB
CSB-PA023992ESR2HU	TNFSF15 Antibody	Human	ELISA, IHC
CSB-RA023992MA1HU	TNFSF15 Recombinant Monoclonal Antibody	Human, Cynomolgus, Mouse	ELISA

TNFSF15 Proteins

TNFSF15 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP023992HU1 CSB-EP023992HU1 CSB-BP023992HU1 CSB-EP023992HU1-B	Recombinant Human Tumor necrosis factor ligand superfamily member 15 (TNFSF15), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP002341HU	Recombinant Human Tumor necrosis factor ligand superfamily member 15 protein (TNFSF15), partial (Active)	E.Coli
CSB-CF023992HU	Recombinant Human Tumor necrosis factor ligand superfamily member 15 (TNFSF15)	in vitro E.coli expression system
CSB-AP004991HU	Recombinant Human Tumor necrosis factor ligand superfamily member 15 (TNFSF15) (Active)	E.coli
CSB-MP023992HU(F2)	Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15) (Active)	Mammalian cell
CSB-MP023992HU1-B	Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active)	Mammalian cell