PTCH2 Antibody, FITC conjugated
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中文名稱：PTCH2兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA896928LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) PTCH2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：patched (Drosophila) homolog 2 antibody; patched homolog 2 (Drosophila) antibody; Protein patched homolog 2 antibody; PTC2 antibody; PTC2_HUMAN antibody; Ptch2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Protein patched homolog 2 protein (793-951AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Plays a role in the control of cellular growth. May have a role in epidermal development. May act as a receptor for Sonic hedgehog (SHH).
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基因功能參考文獻(xiàn)：
- Combined heterozygous germline mutations in PTCH1 and PTCH2 were identified in a patient with embryonal rhabdomyosarcoma. PMID: 29230040
- Frameshift mutation in the PTCH2 gene can cause nevoid basal cell carcinoma syndrome. PMID: 23479190
- PTCH2 isoforms have distinct roles in Hedgehog signalling. PMID: 14613484
- PTCH2 (2157G-->A), a novel missense mutation, underlies NBCCS, resulting in the loss of PTCH2 inhibitory function in the Shh signalling pathway. PMID: 18285427
- A susceptibility locus on 1p32-1p34 for congenital macrostomia in a Chinese family and identification of a novel PTCH2 mutation are reported. PMID: 19208383
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相關(guān)疾?。?/div>Medulloblastoma (MDB); Basal cell carcinoma (BCC)亞細(xì)胞定位：Membrane; Multi-pass membrane protein.蛋白家族：Patched family數(shù)據(jù)庫鏈接：
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