NT5C1A Antibody, FITC conjugated

說明書

中文名稱：

NT5C1A兔多克隆抗體, FITC偶聯
貨號：

CSB-PA866304YC01HU
規格：

￥880
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NT5C1A Polyclonal antibody
Uniprot No.：

Q9BXI3
基因名：

NT5C1A
別名：

5' nucleotidase cytosolic IA antibody; 5NT1A_HUMAN antibody; AMP specific 5' NT antibody; CN I antibody; CN IA antibody; cN-I antibody; cN-IA antibody; CN1 antibody; cN1A antibody; cNI antibody; cNIA antibody; Cytosolic 5' nucleotidase 1A antibody; Cytosolic 5' nucleotidase IA antibody; Cytosolic 5' nucleotidase type 1A antibody; Cytosolic 5''-nucleotidase 1A antibody; Cytosolic 5''-nucleotidase IA antibody; MGC119199 antibody; MGC119201 antibody; NT5C1A antibody; nucleotidase; 5-prime; cytosolic; IA antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Cytosolic 5'-nucleotidase 1A protein (1-368AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
基因功能參考文獻：
1. Individual missense changes in NT5C1A showed considerable variation in response to the different nucleoside analogs tested. PMID: 26906009
2. seropositivity to the NT5c1A antibody is associated with greater motor and functional disability in sporadic inclusion body myositis PMID: 25857661
3. Anti-NT5C1A is a common target of circulating autoantibodies in autoimmune diseases. PMID: 25892010
4. NT5C1A suppression promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle PMID: 21873433
5. overexpression of 5'-nucleotidase inhibits Natural Killer cell cytotoxicity to ameliorate rejection after xenotransplantation PMID: 15888028
6. deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5'-nucleotidase I are regulated in a cell cycle-dependent manner in MOLT-4 cells PMID: 17065091
7. There was no correlation between expression of cN-I and fiber type. PMID: 19352542
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亞細胞定位：

Cytoplasm.
蛋白家族：

5'-nucleotidase type 3 family
組織特異性：

Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
數據庫鏈接：

HGNC: 17819

OMIM: 610525

KEGG: hsa:84618

STRING: 9606.ENSP00000235628

UniGene: Hs.307006

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