WARS1
WARS1，全稱為色氨酰tRNA合成酶1，是一種參與蛋白質合成的重要酶類。該蛋白在細胞內負責將色氨酸氨酰基團連接到對應的tRNA分子上，確保色氨酸在蛋白質合成過程中的正確添加。WARS1蛋白常見別名包括TRY1和TARS1，其結構特征使其能夠高效催化氨酰化反應，對維持蛋白質合成的準確性和效率至關重要。此外，WARS1蛋白還與某些疾病的發生發展密切相關，如神經發育障礙伴小頭畸形等。在藥物研發領域，針對WARS1蛋白的抑制劑已被研究用于治療癌癥和自身免疫性疾病，部分藥物已進入臨床試驗階段，顯示出良好的應用前景。
熱銷產品
Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS1) (CSB-MP025965HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
WARS1 Recombinant Monoclonal Antibody (CSB-RA293319A0HU)
驗證數據
Western Blot
Positive WB detected in: A-431 whole cell lysate(30μg), HeLa whole cell lysate, HL-60 whole cell lysate(30μg)
All lanes: WARS1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53 kDa
Observed band size: 53 kDa
Exposure time: 3min
Overlay Peak curve showing HepG2 cells stained with CSB-RA293319A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
Human tryptophanyl-tRNA synthetase,WARS ELISA Kit (CSB-E11789h)
驗證數據
貨號：CSB-E11789h
規格：96T/48T
靈敏度：0.078 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
WARS1 Antibodies
WARS1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025965GA01HU | WARS Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA025965LA01HU | WARS Antibody | Human | ELISA, IHC |
| CSB-PA025965LB01HU | WARS Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025965LC01HU | WARS Antibody, FITC conjugated | Human | |
| CSB-PA025965LD01HU | WARS Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA293319A0HU | WARS1 Recombinant Monoclonal Antibody | Human | ELISA, WB, FC |
WARS1 Proteins
WARS1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025965HU | Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS) | Yeast |
| CSB-EP025965HU | Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS) | E.coli |
| CSB-BP025965HU CSB-EP025965HU-B |
Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS) | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP025965HU | Recombinant Human Tryptophan--tRNA ligase, cytoplasmic (WARS1) | Mammalian cell |
WARS1 ELISA Kit
WARS1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11789h | Human tryptophanyl-tRNA synthetase,WARS ELISA Kit | serum, plasma, cell lysates, tissue homogenates | 0.078 ng/mL |
