UBE2A
Ubiquitin-conjugating enzyme E2 A is a protein in humans that is encoded by UBE2A gene. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
UBE2A Antibodies
UBE2A for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025438GA01HU | UBE2A Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
UBE2A Proteins
UBE2A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP025438HU CSB-EP025438HU CSB-BP025438HU CSB-MP025438HU CSB-EP025438HU-B |
Recombinant Human Ubiquitin-conjugating enzyme E2 A (UBE2A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
