NEUROG3
NEUROG3，即神經(jīng)生成素3，別名ngn3、Atoh5、NGN-3、Math4B、bHLHa7。NEUROG3是一種堿性螺旋-環(huán)-螺旋（bHLH）家族的轉(zhuǎn)錄因子，參與神經(jīng)發(fā)生和內(nèi)分泌細(xì)胞的分化。NEUROG3通過激活DNA結(jié)合轉(zhuǎn)錄激活因子活性，特異性結(jié)合RNA聚合酶II和雙鏈DNA，參與中樞神經(jīng)系統(tǒng)發(fā)育、正調(diào)控神經(jīng)元分化以及DNA模板轉(zhuǎn)錄調(diào)控。NEUROG3對(duì)于胰腺內(nèi)分泌細(xì)胞的發(fā)育及分化至關(guān)重要，被認(rèn)為是胰腺祖細(xì)胞向內(nèi)分泌細(xì)胞分化的關(guān)鍵調(diào)控因子。NEUROG3的突變與多種疾病相關(guān)，包括先天性吸收不良腹瀉4、葡萄糖不耐受和2型糖尿病。
熱銷產(chǎn)品
Recombinant Human Neurogenin-3 (NEUROG3) (CSB-EP896521HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NEUROG3 Antibody (CSB-PA956774)
驗(yàn)證數(shù)據(jù)
Gel: 12%SDS-PAGE Lysates (from left to right): Mouse liver tissue Amount of lysate: 50μg per lane Primary antibody: 1/250 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.
NEUROG3 Antibodies
NEUROG3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA956774 | NEUROG3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
NEUROG3 Proteins
NEUROG3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP896521HU CSB-BP896521HU CSB-MP896521HU CSB-EP896521HU-B |
Recombinant Human Neurogenin-3 (NEUROG3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP896521HU | Recombinant Human Neurogenin-3 (NEUROG3) | E.coli |
