MAML1
Mastermind-like protein 1 is a protein in humans that is encoded by MAML1 gene. Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
MAML1 Antibodies
MAML1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA838784LA01HU | MAML1 Antibody | Human | ELISA, IHC |
| CSB-PA838784LB01HU | MAML1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA838784LC01HU | MAML1 Antibody, FITC conjugated | Human | |
| CSB-PA838784LD01HU | MAML1 Antibody, Biotin conjugated | Human | ELISA |
MAML1 Proteins
MAML1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP761441MO CSB-EP761441MO CSB-BP761441MO CSB-MP761441MO CSB-EP761441MO-B |
Recombinant Mouse Mastermind-like protein 1 (Maml1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAML1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP838784HU CSB-EP838784HU CSB-BP838784HU CSB-MP838784HU CSB-EP838784HU-B |
Recombinant Human Mastermind-like protein 1 (MAML1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
