GIPR
GIPR，即胃抑制多肽受體，別名PGQTL2。GIPR由人類GIPR基因編碼，該基因位于19號染色體的q13.32區(qū)域。GIPR是一種G蛋白偶聯(lián)受體，其內(nèi)源性配體為葡萄糖依賴性促胰島素釋放多肽（GIP），在脂肪生成、胰島β細胞增殖和胰島素釋放等方面發(fā)揮重要作用，與2型糖尿病、肥胖癥和神經(jīng)退行性疾病相關(guān)。
GIPR與GIP結(jié)合后可激活腺苷酸環(huán)化酶-環(huán)磷酸腺苷-蛋白激酶A通路，促進胰島素分泌。GIPR在調(diào)節(jié)餐后血糖濃度中起到關(guān)鍵作用，在高血糖條件下促進胰島素的分泌；在低血糖條件下刺激胰島α細胞釋放胰高血糖素，從而維持血糖穩(wěn)態(tài)。GIPR的異常表達或功能失調(diào)可能與糖尿病的發(fā)病機制相關(guān)，是糖尿病治療的潛在靶點。
熱銷產(chǎn)品
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GIPR at 2μg/mL can bind Anti-GIPR recombinant antibody (CSB-RA009438MA1HU)，the EC50 is 12.66-13.86 ng/mL.
Recombinant Rat Gastric inhibitory polypeptide receptor (Gipr), partial (Active) (CSB-MP009438RA1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Rat Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO)， the EC50 is 6.946-8.740 ng/mL.
Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr), partial (Active) (CSB-MP009438MO1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Mouse Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO)， the EC50 is 8.622-11.36 ng/mL.
Recombinant Human Gastric inhibitory polypeptide receptor(GIPR),partial (Active) (CSB-MP009438HU1d7)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GIPR at 2μg/mL can bind Anti-GIPR recombinant antibody (CSB-RA009438MA1HU)，the EC50 is 16.18-18.70 ng/mL.
The purity of GIPR was greater than 95% as determined by SEC-HPLC
GIPR Recombinant Monoclonal Antibody (CSB-RA009438MA1HU)
驗證數(shù)據(jù)
The Binding Activity of Macaca fascicularis GIPR with Anti-GIPR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GIPR (CSB-YP4825MOV) at 2 μg/mL can bind Anti-GIPR recombinant antibody. The EC50 is 12.66-13.86 ng/mL.
The Binding Activity of Human GIPR with Anti-GIPR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GIPR (CSB-MP009438HU1d7) at 2 μg/mL can bind Anti-GIPR recombinant antibody. The EC50 is 16.18-18.70 ng/mL.
GIPR Antibodies
GIPR for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA002687 | GIPR Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA057280 | GIPR Antibody | Human,Mouse | ELISA,WB |
| CSB-PA214765 | GIPR Antibody | Human,Mouse | ELISA,WB |
| CSB-PA009438ESR1HU | GIPR Antibody | Human | ELISA, WB, IHC |
| CSB-PA009438ESR2HU | GIPR Antibody | Human | ELISA, IHC, IF |
| CSB-RA009438MA2HU | GIPR Recombinant Monoclonal Antibody | Human | ELISA, WB |
| CSB-RA009438MA1HU | GIPR Recombinant Monoclonal Antibody | Human, Macaca fascicularis | ELISA |
GIPR for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-RA009438MA1MO | Gipr Recombinant Monoclonal Antibody | Mouse, Rat | ELISA |
GIPR Proteins
GIPR Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP009438RA1 CSB-EP009438RA1-B |
Recombinant Rat Gastric inhibitory polypeptide receptor (Gipr), partial | E.coli In Vivo Biotinylation in E.coli |
| CSB-CF009438RA | Recombinant Rat Gastric inhibitory polypeptide receptor (Gipr) | in vitro E.coli expression system |
| CSB-MP009438RA1 | Recombinant Rat Gastric inhibitory polypeptide receptor (Gipr), partial (Active) | Mammalian cell |
GIPR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009438HU1 |
Recombinant Human Gastric inhibitory polypeptide receptor (GIPR), partial | Yeast |
| CSB-CF009438HU | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR) | in vitro E.coli expression system |
| CSB-EP009438HU1 | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR), partial | E.coli |
| CSB-BP009438HU1 | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR), partial | Baculovirus |
| CSB-MP009438HU1 | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR), partial | Mammalian cell |
| CSB-EP009438HU1-B | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR), partial,Biotinylated | E.coli |
| CSB-MP009438HU1d7 | Recombinant Human Gastric inhibitory polypeptide receptor(GIPR),partial (Active) | Mammalian cell |
| CSB-MP009438HU | Recombinant Human Gastric inhibitory polypeptide receptor (GIPR)-VLPs | Mammalian cell |
GIPR Proteins for Mesocricetus auratus (Golden hamster)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009438MRG1 CSB-EP009438MRG1 CSB-BP009438MRG1 CSB-MP009438MRG1 CSB-EP009438MRG1-B |
Recombinant Mesocricetus auratus Gastric inhibitory polypeptide receptor (GIPR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009438MRG | Recombinant Mesocricetus auratus Gastric inhibitory polypeptide receptor (GIPR) | in vitro E.coli expression system |
GIPR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP009438MO1 CSB-EP009438MO1-B |
Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr), partial | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP009438MO1 | Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr), partial | E.coli |
| CSB-MP009438MO1 | Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr), partial (Active) | Mammalian cell |
GIPR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-CF009438MO | Recombinant Mouse Gastric inhibitory polypeptide receptor (Gipr) | in vitro E.coli expression system |
