CD72
CD72，全稱為CD72蛋白，也被稱為Lyb-2或Lyb2。該蛋白在B細胞增殖和分化中扮演關鍵角色，與CD5相互作用，形成具有二硫鍵的同二聚體。CD72蛋白通過酪氨酸磷酸化與PTPN6/SHP-1相互作用，調節(jié)細胞反應。CD72蛋白與B細胞活化和免疫反應密切相關，其功能異常可能與多種疾病有關，如腫瘤和自身免疫性疾病。在藥物研發(fā)方面，針對CD72的抑制劑正在開發(fā)中，旨在調節(jié)B細胞介導的免疫過程，以治療相關疾病。
熱銷產品
Recombinant Human B-cell differentiation antigen CD72 (CD72), partial (CSB-MP004955HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CD72 Antibody (CSB-PA004955LA01HU)
驗證數據
Western Blot
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate
All lanes: CD72 antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa
Immunofluorescence staining of Hela cells with CSB-PA004955LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Human B-cell differentiation antigen CD72(CD72) ELISA kit (CSB-EL004955HU)
驗證數據
貨號：CSB-EL004955HU
規(guī)格：96T/48T
靈敏度：0.225 ng/mL
檢測范圍：0.9 ng/mL-60 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CD72 Antibodies
CD72 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004955GA01HU | CD72 Antibody | Human | ELISA,WB |
| CSB-PA215043 | CD72 Antibody | Human | WB, ELISA |
| CSB-PA004955LA01HU | CD72 Antibody | Human | ELISA, WB, IF |
CD72 Proteins
CD72 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004955MO1 CSB-EP004955MO1 CSB-BP004955MO1 CSB-EP004955MO1-B |
Recombinant Mouse B-cell differentiation antigen CD72 (Cd72), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF004955MO | Recombinant Mouse B-cell differentiation antigen CD72 (Cd72) | in vitro E.coli expression system |
CD72 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004955HU1 CSB-EP004955HU1 CSB-BP004955HU1 CSB-EP004955HU1-B |
Recombinant Human B-cell differentiation antigen CD72 (CD72), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF004955HU | Recombinant Human B-cell differentiation antigen CD72 (CD72) | in vitro E.coli expression system |
| CSB-MP004955HU1 | Recombinant Human B-cell differentiation antigen CD72 (CD72), partial | Mammalian cell |
CD72 ELISA Kit
CD72 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL004955HU | Human B-cell differentiation antigen CD72(CD72) ELISA kit | serum, plasma, tissue homogenates | 0.225 ng/mL |
