CD58
CD58，即細胞表面分化抗原58，別名LFA-3、WLA等。它是一種由CD58基因編碼的糖蛋白，主要表達在多種白細胞表面，包括T細胞、B細胞、自然殺傷(NK)細胞等。CD58的作用機制涉及與T細胞表面的CD2受體結(jié)合，參與免疫細胞間的相互作用，調(diào)節(jié)免疫應答。CD58與CD2的相互作用對于T細胞的激活至關(guān)重要，影響細胞毒性T細胞的殺傷活性和細胞因子的產(chǎn)生。此外，CD58還參與了免疫逃逸機制，某些病原體如單純皰疹病毒(HSV)通過表達與CD58相似的蛋白來逃避宿主的免疫監(jiān)視，是免疫學研究和相關(guān)疾病治療中的一個潛在靶點。
熱銷產(chǎn)品
CD58 Recombinant Monoclonal Antibody (CSB-RA166177A0HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: Raji whole cell lysate, K562 whole cell lysate, Hela whole cell lysate
All lanes: CD58 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29, 27, 26 kDa
Observed band size: 55-70 kDa
CD58 Antibodies
CD58 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004946GA01HU | CD58 Antibody | Human | ELISA,WB |
| CSB-PA004946ESR1HU | CD58 Antibody | Human | ELISA, WB, IHC |
| CSB-PA205850 | CD58 Antibody | Human | ELISA,WB |
| CSB-PA001472 | CD58 Antibody | Human | WB, ELISA |
| CSB-PA005227 | CD58 Antibody | Human | WB, ELISA |
| CSB-RA166177A0HU | CD58 Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD58 Proteins
CD58 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004946HU1 CSB-EP004946HU1 CSB-BP004946HU1 CSB-MP004946HU1 CSB-EP004946HU1-B |
Recombinant Human Lymphocyte function-associated antigen 3 (CD58), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004946HU | Recombinant Human Lymphocyte function-associated antigen 3 (CD58) | in vitro E.coli expression system |
