ACOT7
ACOT7，即酰基輔酶A硫酯酶7，別名Acyl-CoAthioesterase7、ACT、ACH1、BACH、CTE-II、hBACH、LACH、LACH1、MGC1126、RP1-120G22。這是一種在人類細(xì)胞中表達(dá)的酶，屬于酰基輔酶A硫酯酶家族。ACOT7主要在大腦組織和睪丸中高度表達(dá)，它在細(xì)胞質(zhì)中水解長鏈酰基輔酶A，尤其是棕櫚酰輔酶A，生成游離的長鏈脂肪酸和輔酶A。這一過程對(duì)于調(diào)節(jié)脂肪酸代謝和細(xì)胞信號(hào)傳遞至關(guān)重要。ACOT7的活性與神經(jīng)細(xì)胞的健康狀態(tài)密切相關(guān)，其異常表達(dá)可能與內(nèi)側(cè)顳葉癲癇等疾病相關(guān)。ACOT7在細(xì)胞周期進(jìn)程中也發(fā)揮作用，可能通過調(diào)節(jié)PKCζ-p53-p21信號(hào)通路影響細(xì)胞周期。ACOT7不僅在能量代謝中起作用，還是治療神經(jīng)系統(tǒng)疾病和癌癥的潛在靶點(diǎn)。
熱銷產(chǎn)品
ACOT7 Antibody (CSB-PA001169ESR2HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA001169ESR2HU at dilution of 1:100
ACOT7 Antibodies
ACOT7 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001169GA01HU | ACOT7 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA001169ESR2HU | ACOT7 Antibody | Human | ELISA, IHC |
ACOT7 Proteins
ACOT7 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001169HU CSB-EP001169HU CSB-BP001169HU CSB-MP001169HU CSB-EP001169HU-B |
Recombinant Human Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
