ACOT7 Antibody
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中文名稱：ACOT7兔多克隆抗體
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貨號：CSB-PA001169ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA001169ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ACOT7 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：ACH1 antibody; ACOT 7 antibody; ACOT7 antibody; ACT antibody; Acyl CoA thioesterase 7 antibody; Acyl CoA thioesterase long chain antibody; Acyl-CoA thioesterase 7 antibody; BACH antibody; BACH_HUMAN antibody; Brain acyl CoA hydrolase antibody; Brain acyl-CoA hydrolase antibody; CTE-II antibody; CTE-IIa antibody; Cytosolic acyl coenzyme A thioester hydrolase antibody; hBACH antibody; LACH antibody; LACH1 antibody; Long chain acyl-CoA thioester hydrolase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cytosolic acyl coenzyme A thioester hydrolase protein (151-380AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.
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基因功能參考文獻：
- PKCzeta was specifically involved in ACOT7 depletion-mediated cell cycle arrest as an upstream molecule of the p53-p21 signaling pathway in MCF7 human breast carcinoma and A549 human lung carcinoma cells. PMID: 28518146
- WIG1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability of and suppress the translation of ACOT7 mRNA. PMID: 28472401
- the human BACH gene can express long-chain acyl-CoA hydrolase activity in multiple intracellular compartments by generating BACH isoforms with differential localization signals to affect various cellular functions that involve acyl-CoAs PMID: 12435388
- BACH was deranged in hippocampus of mesial temporal lobe epilepsy patients. PMID: 15592755
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亞細胞定位：[Isoform 4]: Cytoplasm, cytosol.; [Isoform 6]: Cytoplasm, cytosol.; [Isoform 1]: Mitochondrion.; [Isoform 5]: Mitochondrion.
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組織特異性：Isoform 4 is expressed exclusively in brain.
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數據庫鏈接：
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