EIF2B1 Antibody
-
中文名稱：EIF2B1兔多克隆抗體
-
貨號：CSB-PA623910ESR1HU
-
規格：￥440
-
圖片：
-
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA623910ESR1HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) EIF2B1 Polyclonal antibody
-
Uniprot No.：
-
基因名：EIF2B1
-
別名：EI2BA_HUMAN antibody; eIF-2B GDP-GTP exchange factor subunit alpha antibody; EIF2B antibody; Eif2b1 antibody; EIF2BA antibody; Eukaryotic translation initiation factor 2B subunit 1 alpha 26kDa antibody; Eukaryotic translation initiation factor 2B subunit alpha antibody; Translation initiation factor eIF-2B subunit alpha antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Translation initiation factor eIF-2B subunit alpha protein (1-305AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, IHC
-
推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
-
基因功能參考文獻：
- Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress PMID: 26112719
- These data emphasize the importance of eIF2Balpha in mediating the eIF2 kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis. PMID: 21795329
- mutational analysis of the eIF2B genes of patients with an antenatal- or early-infantile-onset encephalopathy and an early demise PMID: 14566705
- Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity. PMID: 14993275
- analysis of novel mutations in patients with eIF2B-related disorders PMID: 15776425
- Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon) PMID: 18263758
- The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4. PMID: 18330844
- Crystal structure of the alpha subunit of human translation initiation factor 2B. PMID: 19631657
顯示更多
收起更多
-
相關疾病：Leukodystrophy with vanishing white matter (VWM)
-
蛋白家族：EIF-2B alpha/beta/delta subunits family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
