Recombinant Mouse DnaJ homolog subfamily C member 15 (Dnajc15), partial

中文名稱：

小鼠Dnajc15重組蛋白
貨號：

CSB-YP762363MO1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Dnajc15重組蛋白
貨號：

CSB-EP762363MO1
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Dnajc15重組蛋白
貨號：

CSB-EP762363MO1-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Dnajc15重組蛋白
貨號：

CSB-BP762363MO1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Dnajc15重組蛋白
貨號：

CSB-MP762363MO1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dnajc15
Uniprot No.：

Q78YY6
別名：

Dnajc15; Dnajd1; DnaJ homolog subfamily C member 15
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9. Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP.
基因功能參考文獻：
1. In vivo treatment with an inhibitor of MCJ expression protects liver from acetaminophen-induced liver injury in mouse model at a time when N-acetylcysteine, the standard therapy, has no efficacy. Acetaminophen-induced liver injury progresses through the central participation of MCJ in vitro and in vivo. PMID: 29233977
2. DNAJC15 localizes at the mitochondrial inner membrane, where it interacts preferentially with complex I of the electron transfer chain.DnaJC15 functions as a negative regulator of mitochondrial membrane potential and ATP production. PMID: 23530063
亞細胞定位：

Mitochondrion inner membrane; Single-pass membrane protein.
組織特異性：

Expressed at high levels in liver, heart, at moderate levels in kidney and, at very low levels, in lung (at protein level). High expression levels in testis. Highly expressed in CD8+ T-cells, but barely detectable in CD4+ T-cells (at protein level). Almos
數(shù)據(jù)庫鏈接：

KEGG: mmu:66148

STRING: 10090.ENSMUSP00000022590

UniGene: Mm.248046