Recombinant Human Transcription factor MafF (MAFF)

中文名稱：

人MAFF重組蛋白
貨號：

CSB-YP890935HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人MAFF重組蛋白
貨號：

CSB-EP890935HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人MAFF重組蛋白
貨號：

CSB-EP890935HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MAFF重組蛋白
貨號：

CSB-BP890935HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人MAFF重組蛋白
貨號：

CSB-MP890935HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MAFF
Uniprot No.：

Q9ULX9
別名：

Avian musculoaponeurotic fibrosarcoma virus (v maf) AS42 oncogene, protein F; CTA 447C4.1; hMafF; MAFF; MAFF_HUMAN; OTTHUMP00000199299; Transcription factor MafF; U MAF; U-Maf; V maf avian musculoaponeurotic fibrosarcoma oncogene family, protein F; V maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian); V maf musculoaponeurotic fibrosarcoma oncogene homolog F; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-164
氨基酸序列

MSVDPLSSKA LKIKRELSEN TPHLSDEALM GLSVRELNRH LRGLSAEEVT RLKQRRRTLK NRGYAASCRV KRVCQKEELQ KQKSELEREV DKLARENAAM RLELDALRGK CEALQGFARS VAAARGPATL VAPASVITIV KSTPGSGSGP AHGPDPAHGP ASCS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.
基因功能參考文獻：
1. MAF genes have different levels of biological and genetic relevance. Besides, MAFF and MAFG could be associated with the susceptibility to develop CML. PMID: 24118457
2. MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
3. In myometrial cells we observed an important induction by interleukin 1 beta and a weaker upregulation by tumor necrosis factor, whereas interleukin 6 treatment had no effect. PMID: 16371591
4. Expression of hMafF or MIP alone did not alter basal reporter transcription activity, whereas co-expression of hMafF and MIP activated transcription efficiently. PMID: 16549056
5. Only in the presence of both MIP and hMafF could the nUS2-pLacZi reporter in yeast genome be activated. PMID: 19723544
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亞細胞定位：

Nucleus.
蛋白家族：

BZIP family, Maf subfamily
組織特異性：

Expressed in the term myometrium and kidney.
數據庫鏈接：

HGNC: 6780

OMIM: 604877

KEGG: hsa:23764

STRING: 9606.ENSP00000345393

UniGene: Hs.517617