MAFF Antibody
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中文名稱：MAFF兔多克隆抗體
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貨號：CSB-PA899799
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規格：￥2024
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圖片：
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MAFF antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MAFF Polyclonal antibody
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Uniprot No.：
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基因名：MAFF
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human MAFF.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.
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基因功能參考文獻：
- MAF genes have different levels of biological and genetic relevance. Besides, MAFF and MAFG could be associated with the susceptibility to develop CML. PMID: 24118457
- MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
- In myometrial cells we observed an important induction by interleukin 1 beta and a weaker upregulation by tumor necrosis factor, whereas interleukin 6 treatment had no effect. PMID: 16371591
- Expression of hMafF or MIP alone did not alter basal reporter transcription activity, whereas co-expression of hMafF and MIP activated transcription efficiently. PMID: 16549056
- Only in the presence of both MIP and hMafF could the nUS2-pLacZi reporter in yeast genome be activated. PMID: 19723544
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亞細胞定位：Nucleus.
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蛋白家族：BZIP family, Maf subfamily
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組織特異性：Expressed in the term myometrium and kidney.
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數據庫鏈接：
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