Recombinant Human NFATC2-interacting protein (NFATC2IP)

中文名稱：

人NFATC2IP重組蛋白
貨號：

CSB-YP822758HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人NFATC2IP重組蛋白
貨號：

CSB-EP822758HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人NFATC2IP重組蛋白
貨號：

CSB-EP822758HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NFATC2IP重組蛋白
貨號：

CSB-BP822758HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人NFATC2IP重組蛋白
貨號：

CSB-MP822758HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

NFATC2IP
Uniprot No.：

Q8NCF5
別名：

45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; cytoplasmic 2-interacting protein; ESC2; NF2IP_HUMAN; NFAT-interacting protein, 45-KD; NFATC2-interacting protein; Nfatc2ip; NIP45; Nuclear factor of activated T-cells; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-419
氨基酸序列

MAEPVGKRGR WSGGSGAGRG GRGGWGGRGR RPRAQRSPSR GTLDVVSVDL VTDSDEEILE VATARGAADE VEVEPPEPPG PVASRDNSNS DSEGEDRRPA GPPREPVRRR RRLVLDPGEA PLVPVYSGKV KSSLRLIPDD LSLLKLYPPG DEEEAELADS SGLYHEGSPS PGSPWKTKLR TKDKEEKKKT EFLDLDNSPL SPPSPRTKSR THTRALKKLS EVNKRLQDLR SCLSPKPPQG QEQQGQEDEV VLVEGPTLPE TPRLFPLKIR CRADLVRLPL RMSEPLQSVV DHMATHLGVS PSRILLLFGE TELSPTATPR TLKLGVADII DCVVLTSSPE ATETSQQLQL RVQGKEKHQT LEVSLSRDSP LKTLMSHYEE AMGLSGRKLS FFFDGTKLSG RELPADLGME SGDLIEVWG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
基因功能參考文獻：
1. ZBTB25 functions as a negative regulator of nuclear factor of activated T cells (NF-AT) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes. PMID: 20410506
亞細胞定位：

Nucleus. Cytoplasm.
數據庫鏈接：

HGNC: 25906

OMIM: 614525

KEGG: hsa:84901

STRING: 9606.ENSP00000324792

UniGene: Hs.513470