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中文名稱：
NFATC2IP兔多克隆抗體
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貨號：
CSB-PA070052
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規格：
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其他：
產品詳情
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Uniprot No.：
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基因名：
NFATC2IP
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別名：
45 kDa NF-AT-interacting protein antibody; 45 kDa NFAT-interacting protein antibody; cytoplasmic 2-interacting protein antibody; ESC2 antibody; NF2IP_HUMAN antibody; NFAT-interacting protein, 45-KD antibody; NFATC2-interacting protein antibody; Nfatc2ip antibody; NIP45 antibody; Nuclear factor of activated T-cells antibody; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein antibody; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein antibody; RAD60 antibody
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Synthesized peptide derived from the Internal region of Human NFATc2IP.
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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抗體亞型：
IgG
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純化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：
Liquid
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應用范圍：
WB, ELISA
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推薦稀釋比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| ELISA |
1:10000 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
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基因功能參考文獻：
- ZBTB25 functions as a negative regulator of nuclear factor of activated T cells (NF-AT) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes. PMID: 20410506
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亞細胞定位：
Nucleus. Cytoplasm.
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數據庫鏈接：
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