Recombinant Human Beta-1,4-galactosyltransferase 5 (B4GALT5), partial

中文名稱：

Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial
貨號：

CSB-YP527356HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial
貨號：

CSB-EP527356HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial
貨號：

CSB-EP527356HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial
貨號：

CSB-BP527356HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Beta-1,4-galactosyltransferase 5(B4GALT5),partial
貨號：

CSB-MP527356HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

B4GALT5
Uniprot No.：

O43286
別名：

4-galactosyltransferase 5; 4-GalT II; 4-GalTase 5; B4Gal T5; b4Gal-T5; B4galt5; B4GT5_HUMAN; Beta 1 4 galactosyltransferase 5; Beta 1 4 galactosyltransferase V; Beta 1 4 GalT II; Beta 1 4 GalT IV; Beta 1 4 GalTase 5; Beta-1; Beta-1,4-galactosyltransferase 5; Beta-1,4-GalT II; Beta-1,4-GalTase 5; Beta4 GALT IV; Beta4Gal T5; Beta4Gal-T5; Beta4GalT V; gt V; gtV; MGC138470; UDP Gal:beta GlcNAc beta 1 4 galactosyltransferase 5; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase 5; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase polypeptide 5; UDP galactose:beta N acetylglucosamine beta 1 4 galactosyltransferase 5; UDP-Gal:beta-GlcNAc beta-1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.
基因功能參考文獻(xiàn)：
1. 2.3-kb 5'-flanking region of the human beta-1,4-GalT V gene was cloned and the region -116/-18 relative to the transcription start site as that having promoter activity. PMID: 15263012
2. B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. PMID: 23744354
3. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 and Ets-1 in cancer cells.(review) PMID: 22687727
4. These data reveal a critical role of beta1,4GalT V in the self-renewal and tumorigenicity of glioma-initiating cells. PMID: 20417617
5. Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line PMID: 12385586
6. results suggest that GalT V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy PMID: 16461357
7. Ets-1 enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 gene in cancer cells PMID: 17656364
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亞細(xì)胞定位：

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus.
蛋白家族：

Glycosyltransferase 7 family
組織特異性：

Ubiquitously expressed.
數(shù)據(jù)庫鏈接：

HGNC: 928

OMIM: 604016

KEGG: hsa:9334

STRING: 9606.ENSP00000360776

UniGene: Hs.370487