B4GALT5 Antibody

說明書

中文名稱：

B4GALT5兔多克隆抗體
貨號：

CSB-PA004624
規格：

￥1090
圖片：
Western Blot analysis of 293 cells using β-1,4-Gal-T5 Polyclonal Antibody

Western Blot analysis of K562 cells using β-1,4-Gal-T5 Polyclonal Antibody
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

Uniprot No.：

O43286
基因名：

B4GALT5
別名：

4-galactosyltransferase 5 antibody; 4-GalT II antibody; 4-GalTase 5 antibody; B4Gal T5 antibody; b4Gal-T5 antibody; B4galt5 antibody; B4GT5_HUMAN antibody; Beta 1 4 galactosyltransferase 5 antibody; Beta 1 4 galactosyltransferase V antibody; Beta 1 4 GalT II antibody; Beta 1 4 GalT IV antibody; Beta 1 4 GalTase 5 antibody; Beta-1 antibody; Beta-1,4-galactosyltransferase 5 antibody; Beta-1,4-GalT II antibody; Beta-1,4-GalTase 5 antibody; Beta4 GALT IV antibody; Beta4Gal T5 antibody; Beta4Gal-T5 antibody; Beta4GalT V antibody; gt V antibody; gtV antibody; MGC138470 antibody; UDP Gal:beta GlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase polypeptide 5 antibody; UDP galactose:beta N acetylglucosamine beta 1 4 galactosyltransferase 5 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the C-terminal region of Human β-1,4-Gal-T5.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.
基因功能參考文獻：
1. 2.3-kb 5'-flanking region of the human beta-1,4-GalT V gene was cloned and the region -116/-18 relative to the transcription start site as that having promoter activity. PMID: 15263012
2. B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. PMID: 23744354
3. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 and Ets-1 in cancer cells.(review) PMID: 22687727
4. These data reveal a critical role of beta1,4GalT V in the self-renewal and tumorigenicity of glioma-initiating cells. PMID: 20417617
5. Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line PMID: 12385586
6. results suggest that GalT V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy PMID: 16461357
7. Ets-1 enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 gene in cancer cells PMID: 17656364
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亞細胞定位：

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus.
蛋白家族：

Glycosyltransferase 7 family
組織特異性：

Ubiquitously expressed.
數據庫鏈接：

HGNC: 928

OMIM: 604016

KEGG: hsa:9334

STRING: 9606.ENSP00000360776

UniGene: Hs.370487

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