Recombinant Human BTB/POZ domain-containing protein KCTD1 (KCTD1)

中文名稱：

人KCTD1重組蛋白
貨號：

CSB-YP744477HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人KCTD1重組蛋白
貨號：

CSB-EP744477HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人KCTD1重組蛋白
貨號：

CSB-EP744477HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人KCTD1重組蛋白
貨號：

CSB-BP744477HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人KCTD1重組蛋白
貨號：

CSB-MP744477HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

KCTD1
Uniprot No.：

Q719H9
別名：

KCTD1; C18orf5; BTB/POZ domain-containing protein KCTD1; Potassium channel tetramerization domain-containing protein 1
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-257
氨基酸序列

MSRPLITRSP ASPLNNQGIP TPAQLTKSNA PVHIDVGGHM YTSSLATLTK YPESRIGRLF DGTEPIVLDS LKQHYFIDRD GQMFRYILNF LRTSKLLIPD DFKDYTLLYE EAKYFQLQPM LLEMERWKQD RETGRFSRPC ECLVVRVAPD LGERITLSGD KSLIEEVFPE IGDVMCNSVN AGWNHDSTHV IRFPLNGYCH LNSVQVLERL QQRGFEIVGS CGGGVDSSQF SEYVLRRELR RTPRVPSVIR IKQEPLD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
基因功能參考文獻：
1. results reveal a novel role for Cu(2+) in determining the structure and function of KCTD1 PMID: 27596723
2. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding. PMID: 26334369
3. KCTD1 functions as a novel inhibitor of Wnt signaling p PMID: 24736394
4. Mutations in KCTD1 cause scalp-ear-nipple syndrome. PMID: 23541344
5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
6. indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 family, especially for AP-2alpha PMID: 19115315
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相關疾病：

Scalp-ear-nipple syndrome (SENS)
亞細胞定位：

Nucleus.
組織特異性：

Expressed in mammary gland, kidney, brain and ovary.
數據庫鏈接：

HGNC: 18249

OMIM: 181270

KEGG: hsa:284252

STRING: 9606.ENSP00000408405

UniGene: Hs.526630