KCTD1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) KCTD1 Polyclonal antibody
Uniprot No.：

Q719H9
基因名：

KCTD1
別名：

KCTD1 antibody; C18orf5 antibody; BTB/POZ domain-containing protein KCTD1 antibody; Potassium channel tetramerization domain-containing protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human BTB/POZ domain-containing protein KCTD1 protein (1-257AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
基因功能參考文獻：
1. results reveal a novel role for Cu(2+) in determining the structure and function of KCTD1 PMID: 27596723
2. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding. PMID: 26334369
3. KCTD1 functions as a novel inhibitor of Wnt signaling p PMID: 24736394
4. Mutations in KCTD1 cause scalp-ear-nipple syndrome. PMID: 23541344
5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
6. indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 family, especially for AP-2alpha PMID: 19115315
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相關疾病：

Scalp-ear-nipple syndrome (SENS)
亞細胞定位：

Nucleus.
組織特異性：

Expressed in mammary gland, kidney, brain and ovary.
數據庫鏈接：

HGNC: 18249

OMIM: 181270

KEGG: hsa:284252

STRING: 9606.ENSP00000408405

UniGene: Hs.526630

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