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中文名稱：secG兔多克隆抗體
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貨號：CSB-PA314852XA01ENV
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規格：￥880
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圖片：
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Western Blot
Positive WB detected in: recombinant protein
All lanes:secG Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Escherichia coli (strain K12) secG Antibody Polyclonal antibody
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Uniprot No.：
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基因名：secG Antibody
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別名：Protein-export membrane protein SecG (P12) (Preprotein translocase band 1 subunit) secG b3175 JW3142
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宿主：Rabbit
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反應種屬：Escherichia coli (strain K12)
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免疫原：Recombinant Escherichia coli (strain K12) secG protein (67-110aa)
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免疫原種屬：Escherichia coli (strain K12)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Subunit of the protein translocation channel SecYEG. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY. Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.
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基因功能參考文獻：
- Authors show that SecG plays a critical role for the residual export mediated by mutant signal sequences and that the SecYE dimer can often be detected only in the presence of SecG. PMID: 25404704
- The hydrophobicity threshold for SecYEG-mediated cell membrane insertion is distinctly lower than that for Sec61-mediated insertion. PMID: 23659793
- Data show that ribosome binding is sufficient to open the SecYEG channel. PMID: 23645666
- Data indicate taht SecG inversion occurs only when MPIase associates with SecYEG. PMID: 23716687
- Charge composition features of model single-span membrane proteins that determine selection of YidC and SecYEG translocase pathways in Escherichia coli PMID: 23355473
- analysis of conformational dynamics of the plug domain of the SecYEG protein-conducting channel PMID: 22033919
- SecYEG-bound SecA undergoes ATP-dependent conformational changes that are not observed for soluble SecA. PMID: 15850376
- cryo-electron microscopy reconstruction of the E. coli protein-conducting channel, SecYEG, complexed with the ribosome and a nascent chain containing a signal anchor PMID: 16292303
- cotranslational targeting of a protein to the E. coli SecYEG complex does not ensure its export but that export also depends on a subsequent event that involves sequences both within and just beyond the signal peptide PMID: 19211555
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亞細胞定位：Cell inner membrane; Multi-pass membrane protein.
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蛋白家族：SecG family
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數據庫鏈接：
KEGG: ecj:JW3142
STRING: 316385.ECDH10B_3349
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