ZIC5 Antibody

中文名稱：

ZIC5兔多克隆抗體
貨號：

CSB-PA850433LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA850433LA01HU diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ZIC5 Polyclonal antibody
Uniprot No.：

Q96T25
基因名：

ZIC5
別名：

zic5 antibody; ZIC5_HUMAN antibody; Zinc finger protein of the cerebellum 5 antibody; Zinc finger protein ZIC 5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Zinc finger protein ZIC 5 protein (217-276AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，ZIC5 Antibody (CSB-PA850433LA01HU)，的標記方式是Non-conjugated。對于ZIC5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應用
HRP	CSB-PA850433LB01HU	ZIC5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA850433LC01HU	ZIC5 Antibody, FITC conjugated
Biotin	CSB-PA850433LD01HU	ZIC5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.
基因功能參考文獻：
1. hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability. PMID: 29605301
2. ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells PMID: 29024195
3. ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression PMID: 27663664
4. ZIC1, ZIC2, and ZIC5 may have roles in meningiomas PMID: 20199689
5. the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates. PMID: 20683983
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亞細胞定位：

Nucleus.
蛋白家族：

GLI C2H2-type zinc-finger protein family
數(shù)據(jù)庫鏈接：

HGNC: 20322

OMIM: 617896

KEGG: hsa:85416

STRING: 9606.ENSP00000267294

UniGene: Hs.508570

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