ZIC5 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZIC5 Polyclonal antibody
Uniprot No.：

Q96T25
基因名：

ZIC5
別名：

zic5 antibody; ZIC5_HUMAN antibody; Zinc finger protein of the cerebellum 5 antibody; Zinc finger protein ZIC 5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Zinc finger protein ZIC 5 protein (217-276AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.
基因功能參考文獻：
1. hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability. PMID: 29605301
2. ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells PMID: 29024195
3. ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression PMID: 27663664
4. ZIC1, ZIC2, and ZIC5 may have roles in meningiomas PMID: 20199689
5. the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates. PMID: 20683983
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亞細胞定位：

Nucleus.
蛋白家族：

GLI C2H2-type zinc-finger protein family
數據庫鏈接：

HGNC: 20322

OMIM: 617896

KEGG: hsa:85416

STRING: 9606.ENSP00000267294

UniGene: Hs.508570

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