ZBTB20 Antibody

說明書

中文名稱：

ZBTB20兔多克隆抗體
貨號：

CSB-PA867198ESR2HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA867198ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA867198ESR2HU at dilution of 1:100
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZBTB20 Polyclonal antibody
Uniprot No.：

Q9HC78
基因名：

ZBTB20
別名：

Dendritic derived BTB/POZ zinc finger protein antibody; Dendritic-derived BTB/POZ zinc finger protein antibody; DKFZp566F123 antibody; DPZF antibody; HOF antibody; ODA 8S antibody; OTTHUMP00000215066 antibody; OTTHUMP00000215067 antibody; OTTHUMP00000215069 antibody; OTTHUMP00000215071 antibody; ZBT20_HUMAN antibody; Zbtb20 antibody; zinc finger 288 antibody; zinc finger and BTB domain containing 20 antibody; Zinc finger and BTB domain-containing protein 20 antibody; Zinc finger protein 288 antibody; ZNF288 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Zinc finger and BTB domain-containing protein 20 protein (100-400AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
基因功能參考文獻：
1. ZBTB20 knockdown inhibited glioblastoma cell proliferation, migration, and invasion. PMID: 30099442
2. High ZBTB20 expression is associated with hepatocellular carcinoma. PMID: 26893361
3. We report a boy with intellectual disability carrying two de novo missense mutations in the last exon of ZBTB20 (Ser616Phe and Gly741Arg; both previously unreported). One of them, Ser616Phe, affects an amino acid located in one of the C2H2 zing-fingers involved in DNA-binding and close to other missense mutations already described. Reverse phenotyping showed that this patient presents with classic features of Primrose syn PMID: 27061120
4. ZBTB20 rs9841504 polymorphism is a protective factor for gastric cancer rather than esophageal cancer. PMID: 27646774
5. 3q13.31 microdeletion-based dosage imbalance of ZBTB20 linked to a range of neurodevelopmental, cognitive and psychiatric disorders, likely mediated by dysregulation of multiple ZBTB20 target genes. PMID: 25062845
6. Major depressive disorder is associated with significant hypermethylation within the coding region of ZBTB20. PMID: 24694013
7. important role for ZBTB20 in controlling NSCLC development PMID: 25311537
8. Missense mutations in ZBTB20 underlie Primrose syndrome. PMID: 25017102
9. This study disclosed Zbtb20-mediated transcriptional repressor mechanism may be involved in development of the human archicortex. PMID: 23283686
10. Polymorphism in ZBTB20 gene is associated with gastric cancer. PMID: 23861218
11. We identified new susceptibility loci for non-cardia gastric cancer at 3q13.31: rs9841504 in ZBTB20 PMID: 22037551
12. ZBTB20 mRNA & protein expression were elevated significantly in HCC tissues compared with the paired non-tumor tissues & normal liver. HCC recurrence or metastasis increased & disease-free survival decreased with high ZBTB20 expression. PMID: 21702992
13. Misexpression of Zbtb20 in transgenic mice converts the normal cytoarchitectonic organization of the subiculum, postsubiculum, and granular retrosplenial cortex to a CA1-like stratum pyramidale. PMID: 19955470
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相關疾病：

Primrose syndrome (PRIMS)
亞細胞定位：

Nucleus.
組織特異性：

Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver.
數據庫鏈接：

HGNC: 13503

OMIM: 259050

KEGG: hsa:26137

STRING: 9606.ENSP00000419153

UniGene: Hs.202577

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