ZBTB20 Antibody
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中文名稱：ZBTB20兔多克隆抗體
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貨號：CSB-PA867198ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA867198ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ZBTB20 Polyclonal antibody
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Uniprot No.：
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基因名：ZBTB20
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別名：Dendritic derived BTB/POZ zinc finger protein antibody; Dendritic-derived BTB/POZ zinc finger protein antibody; DKFZp566F123 antibody; DPZF antibody; HOF antibody; ODA 8S antibody; OTTHUMP00000215066 antibody; OTTHUMP00000215067 antibody; OTTHUMP00000215069 antibody; OTTHUMP00000215071 antibody; ZBT20_HUMAN antibody; Zbtb20 antibody; zinc finger 288 antibody; zinc finger and BTB domain containing 20 antibody; Zinc finger and BTB domain-containing protein 20 antibody; Zinc finger protein 288 antibody; ZNF288 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Zinc finger and BTB domain-containing protein 20 protein (100-400AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
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基因功能參考文獻：
- ZBTB20 knockdown inhibited glioblastoma cell proliferation, migration, and invasion. PMID: 30099442
- High ZBTB20 expression is associated with hepatocellular carcinoma. PMID: 26893361
- We report a boy with intellectual disability carrying two de novo missense mutations in the last exon of ZBTB20 (Ser616Phe and Gly741Arg; both previously unreported). One of them, Ser616Phe, affects an amino acid located in one of the C2H2 zing-fingers involved in DNA-binding and close to other missense mutations already described. Reverse phenotyping showed that this patient presents with classic features of Primrose syn PMID: 27061120
- ZBTB20 rs9841504 polymorphism is a protective factor for gastric cancer rather than esophageal cancer. PMID: 27646774
- 3q13.31 microdeletion-based dosage imbalance of ZBTB20 linked to a range of neurodevelopmental, cognitive and psychiatric disorders, likely mediated by dysregulation of multiple ZBTB20 target genes. PMID: 25062845
- Major depressive disorder is associated with significant hypermethylation within the coding region of ZBTB20. PMID: 24694013
- important role for ZBTB20 in controlling NSCLC development PMID: 25311537
- Missense mutations in ZBTB20 underlie Primrose syndrome. PMID: 25017102
- This study disclosed Zbtb20-mediated transcriptional repressor mechanism may be involved in development of the human archicortex. PMID: 23283686
- Polymorphism in ZBTB20 gene is associated with gastric cancer. PMID: 23861218
- We identified new susceptibility loci for non-cardia gastric cancer at 3q13.31: rs9841504 in ZBTB20 PMID: 22037551
- ZBTB20 mRNA & protein expression were elevated significantly in HCC tissues compared with the paired non-tumor tissues & normal liver. HCC recurrence or metastasis increased & disease-free survival decreased with high ZBTB20 expression. PMID: 21702992
- Misexpression of Zbtb20 in transgenic mice converts the normal cytoarchitectonic organization of the subiculum, postsubiculum, and granular retrosplenial cortex to a CA1-like stratum pyramidale. PMID: 19955470
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相關疾病：Primrose syndrome (PRIMS)
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亞細胞定位：Nucleus.
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組織特異性：Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver.
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數據庫鏈接：
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