YY1AP1 Antibody
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中文名稱：YY1AP1兔多克隆抗體
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貨號：CSB-PA884488LA01HU
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規格：￥440
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圖片：
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IHC image of CSB-PA884488LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. -
Immunofluorescence staining of HepG2 cells with CSB-PA884488LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). -
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate, Hela whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate, 293 whole cell lysate
All lanes: YY1AP1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 88, 84, 82, 81, 76, 80, 51, 96, 98 kDa
Observed band size: 88 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) YY1AP1 Polyclonal antibody
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Uniprot No.：
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基因名：YY1AP1
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別名：FLJ10875 antibody; FLJ13914 antibody; GRNG antibody; HCCA1 antibody; HCCA2 antibody; Hepatocellular carcinoma susceptibility protein antibody; Hepatocellular carcinoma-associated protein 2 antibody; OTTHUMP00000033475 antibody; OTTHUMP00000033476 antibody; OTTHUMP00000200831 antibody; OTTHUMP00000200832 antibody; OTTHUMP00000200833 antibody; OTTHUMP00000200836 antibody; YAP antibody; YY1-associated protein 1 antibody; YY1AP antibody; YY1AP1 antibody; YYAP1_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human YY1-associated protein 1 protein (335-466AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，YY1AP1 Antibody (CSB-PA884488LA01HU)，的標記方式是Non-conjugated。對于YY1AP1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:200-1:500 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.
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基因功能參考文獻：
- Data indicate WW-binding protein 2 (WBP2) as an important co-factor of YY1 associated protein 1 (YAP) that enhances YAP/TEAD-mediated gene transcription. PMID: 28332498
- Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. PMID: 27939641
- YY1AP1 may serve as a key molecular target for EpCAM(+) AFP(+) HCC subtype PMID: 25597408
- human liver cancer associated gene PMID: 11856496
- YY1AP is a novel co-activator of YY1 PMID: 14744866
- HCCA2 may play a novel role in cell cycle regulation. PMID: 17541814
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相關疾?。?/div>Grange syndrome (GRNG)亞細胞定位：Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.組織特異性：Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.數據庫鏈接：
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