TUBB2A Antibody
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中文名稱：TUBB2A兔多克隆抗體
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貨號：CSB-PA000384
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規格：￥1090
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圖片：
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Western blot analysis of 1) Hela, 2) 3T3, 3) Rat Kidney tissue, diluted at 1:3000.
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：TUBB2A antibody; TUBB2 antibody; Tubulin beta-2A chain antibody; Tubulin beta class IIa antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic Peptide
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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產品提供形式：Liquid
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應用范圍：WB
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推薦稀釋比：
Application Recommended Dilution WB 1:2000-5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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基因功能參考文獻：
- TUBB2A missense mutation is associated with arthrogryposis multiplex congenita, brain abnormalities, and severe developmental delay. PMID: 28840640
- study associates mutations in TUBB2A with the spectrum of "tubulinopathy" phenotypes PMID: 24702957
- This is the first study showing that paclitaxel neuropathy risk is influenced by polymorphisms regulating the expression of a beta-tubulin gene. PMID: 22718863
- Class II beta-tubulin may be very useful for immunohistochemical diagnosis of classical Hodgkin's lymphoma. PMID: 22449234
- Data suggest that the increased betaII- and betaIII-tubulin contributed significantly to the resistance phenotype. PMID: 22180309
- lack of mutations in early stage lung cancer PMID: 12209967
- Mutations of the beta-tubulin gene, which might be a contraindication for chemotherapy based on taxans, were very rare events in gastric cancer. PMID: 12861402
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相關疾病：Cortical dysplasia, complex, with other brain malformations 5 (CDCBM5)
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亞細胞定位：Cytoplasm, cytoskeleton.
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蛋白家族：Tubulin family
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組織特異性：High expression in brain, where it represents 30% of all beta-tubulins.
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數據庫鏈接：
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