TNFSF8 Antibody
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中文名稱：TNFSF8兔多克隆抗體
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貨號：CSB-PA951710
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規格：￥2024
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圖片：
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Western blot analysis of extracts from RAW264.7 cells, using CD153 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TNFSF8 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：TNFSF8; CD30L; CD30LG; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD antigen CD153
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human CD153.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
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基因功能參考文獻：
- circulant sCD30L is functionally active and that it may favor persistence of active inflammation by inducing apoptosis of CD30(+)T cells, known to down-modulate inflammation in rheumatoid synovitis. PMID: 24447865
- TNFSF8 is an important leprosy T1R susceptibility gene. PMID: 25320285
- The heritability of IgA levels is moderate and can partly be attributable to common variation in the CD30L locus. PMID: 24676358
- The TNFSF8 polymorphisms rs927374 and rs2295800 were associated with neutrophil count. This finding suggests that post-MI inflammatory response is genetically modulated. PMID: 22033252
- Positional candidate gene screening in the SPA2 locus allowed us to identify and replicate an association between a rare SNP located in TNFSF8 and spondylarthritis. PMID: 21480186
- a possible role of novel TNFSF8 variants in susceptibility to lung cancer. PMID: 21292647
- capability to up-regulate expression of CD30, release of soluble CD30 and production of IL-4 in pre-activated T cells upon co-culture PMID: 11728464
- Mast cells were found to be the predominant CD30 ligand-positive (CD30L-positive) cell in the chronic inflammatory skin diseases psoriasis and atopic dermatitis. PMID: 16964309
- CD153 antigen was expressed by synovial mast cells, and correlated with serum levels, in Rheumatoid Arthritis patients PMID: 19208589
- Single nucleotide polymorphism in TNFSF8 gene is associated with bone disease in myeloma. PMID: 19657367
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亞細胞定位：Membrane; Single-pass type II membrane protein.
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蛋白家族：Tumor necrosis factor family
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數據庫鏈接：
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