TEFM Antibody

中文名稱：

TEFM兔多克隆抗體
貨號(hào)：

CSB-PA857011LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA857011LA01HU diluted at 1:400 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) TEFM Polyclonal antibody
Uniprot No.：

Q96QE5
基因名：

TEFM
別名：

TEFM antibody; C17orf42 antibody; Transcription elongation factor antibody; mitochondrial antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Transcription elongation factor, mitochondrial protein (36-165AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，TEFM Antibody (CSB-PA857011LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于TEFM Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA857011LB01HU	TEFM Antibody, HRP conjugated	ELISA
FITC	CSB-PA857011LC01HU	TEFM Antibody, FITC conjugated
Biotin	CSB-PA857011LD01HU	TEFM Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
基因功能參考文獻(xiàn)：
1. Data provide insights into target specificity of TEFM and mechanisms by which it regulates the switch between transcription and replication of mitochondrial DNA. PMID: 29033127
2. Data indicate transcription elongation factor (TEFM) as an essential component of the mitochondrial transcription machinery. PMID: 25690892
3. study found interaction of TEFM with mitochondrial RNA polymerase and nascent transcript prevents generation of replication primers and increases transcription processivity and serves as a molecular switch between replication and transcription, which appear to be mutually exclusive processes in mitochondria PMID: 25635099
4. The TEFM protein is proposed to be a critical component of the transcription apparatus of human mitochondria. PMID: 21278163
亞細(xì)胞定位：

Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
蛋白家族：

TEFM family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 26223

OMIM: 616422

KEGG: hsa:79736

UniGene: Hs.317340

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