SUMF2 Antibody
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中文名稱：SUMF2兔多克隆抗體
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貨號(hào)：CSB-PA022947GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：SUMF2
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別名：SUMF2 antibody; PSEC0171 antibody; UNQ1968/PRO4500 antibody; Inactive C-alpha-formylglycine-generating enzyme 2 antibody; Paralog of formylglycine-generating enzyme antibody; pFGE antibody; Sulfatase-modifying factor 2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human SUMF2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1.
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基因功能參考文獻(xiàn)：
- SUMF2 interacted with IL-13 and inhibited IL-13 secretion in bronchial smooth muscle cells and lymphocytes, which was independent of IL-13 glycosylation PMID: 19739097
- structural analysis of human pFGE by X-ray crystallography [pFGE] PMID: 15687489
- pFGE (SUMF2) is the paralog of the Calpha-formylglycine-generating enzyme PMID: 15708861
- SUMF2 interacts with sulphatase-modifying factor 1 to regulate sulphatase activities. PMID: 15962010
- pFGE is retained in the ER through its C-terminal tetrapeptide PGEL, a noncanonical variant of the classic KDEL ER-retention signal. PMID: 18266766
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亞細(xì)胞定位：Endoplasmic reticulum lumen.
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蛋白家族：Sulfatase-modifying factor family
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組織特異性：Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta.
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數(shù)據(jù)庫(kù)鏈接：
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