SLIT3 Antibody
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中文名稱：SLIT3兔多克隆抗體
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貨號：CSB-PA270713
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA270713(SLIT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA270713(SLIT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：SLIT3
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別名：FLJ10764 antibody; KIAA0814 antibody; MEGF 5 antibody; MEGF5 antibody; Multiple EGF-like domains protein 5 antibody; Multiple epidermal growth factor like domains 5 antibody; Multiple epidermal growth factor-like domains protein 5 antibody; SLIL 2 antibody; SLIL2 antibody; SLIT 1 antibody; Slit 2 antibody; Slit 3 antibody; Slit homolog 3 (Drosophila) antibody; Slit homolog 3 antibody; Slit homolog 3 protein antibody; Slit-3 antibody; SLIT1 antibody; Slit2 antibody; Slit3 antibody; SLIT3_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human SLIT3
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
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基因功能參考文獻：
- Overexpression of Slit3 induces its tumor suppressive effects in Breast cancer. PMID: 26542734
- Results show that silencing of Slit3 promoted proliferation, migration and invasion of A549 cells and induced epithelial-mesenchymal transition suggesting that Slit3 functions as a tumor suppressor in lung carcinoma. PMID: 26045181
- Estrogen-dependent expression of SLIT3 may play a key role in regulating nerve-vessel interactions within the complex microenvironment of endometriosis lesions. PMID: 25051436
- SLIT3 is increased with labour, and both amnion and myometrial studies describe a pro-inflammatory effect of SLIT3 in these tissues. PMID: 24286238
- High SLIT3 expression is associated with high-grade gliomas. PMID: 24158112
- SLIT3-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo. PMID: 24090675
- results implicate the involvement of miR-218-2 and its host gene SLIT3 in thyroid cancer cell invasion, migration, and proliferation PMID: 23720784
- Slit3 treatment increased the in vivo homing efficiency of CD34 HSPCs to the BM in NOD/SCID mice, whereas Slit3-exposed HSPC migration in vitro was inhibited. Results support a role for Slit3 in human HSPC migration in vitro and homing in vivo. PMID: 22614124
- SLIT3 duplication on 5q35.1 predisposes to major depressive disorder PMID: 21152026
- The chemorepellent Slit3 promotes monocyte migration. PMID: 21078908
- Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis. PMID: 20298552
- Many variants in SLIT3 tend to associate with schizophrenia susceptibility in the Chinese Han population. PMID: 15231749
- data suggest that Slit proteins play a key role in guiding dorsally projecting cranial motoneurons and in facilitating their neural tube exit PMID: 16162649
- In fetal and embryonic stem cell cultures Slit-3 inhibited neurite outgrowth. PMID: 16840550
- functions to promote angiogenesis in coordinating organogenesis during embryonic development PMID: 19741192
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亞細胞定位：Secreted.
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組織特異性：Predominantly expressed in thyroid.
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數據庫鏈接：
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