RASSF4 Antibody, Biotin conjugated
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中文名稱：RASSF4兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA880956LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RASSF4 Polyclonal antibody
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Uniprot No.：
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基因名：RASSF4
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別名：3830411C14Rik antibody; AD037 antibody; AI586137 antibody; MGC105606 antibody; MGC44914 antibody; OTTHUMP00000019493 antibody; Ras association (RalGDS/AF 6) domain family 4 antibody; Ras association (RalGDS/AF 6) domain family member 4 antibody; Ras association domain containing protein 4 antibody; Ras association domain family 4 antibody; Ras association domain-containing protein 4 antibody; RASF4_HUMAN antibody; RASSF 4 antibody; Rassf4 antibody; RP11-285G1.4 antibody; Tumor suppressor RASSF4 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Ras association domain-containing protein 4 protein (65-180AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
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基因功能參考文獻：
- RASSF4 controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes. PMID: 28600435
- RASSF4 overexpression inhibits proliferation, invasion, EMT, and Wnt signaling pathway in osteosarcoma cells. PMID: 28081736
- the present study suggested that RASSF4 serves as an important tumor suppressor in human nonsmall cell lung cancer . PMID: 26526576
- RASSF4 promotes EV71 replication and the production of viral progeny to accelerate the inhibition of the phosphorylation of AKT. PMID: 25701784
- expression of SPRR1B is upregulated in oral CSCs/CICs and SPRR1B has a role in cell growth by suppression of RASSF4 PMID: 23954638
- Single nucleotide polymorphism in RASSF4 gene is associated with acute lymphoblastic leukemia. PMID: 19066393
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組織特異性：Widely expressed. Frequently down-regulated in tumor cell lines.
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數據庫鏈接：
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