RAB3GAP2 Antibody
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中文名稱：RAB3GAP2兔多克隆抗體
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貨號：CSB-PA215524
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規格：￥2024
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圖片：
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Western blot analysis of extracts from COS cells, using RAB3GAP2 antibody. -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using RAB3GAP2 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RAB3GAP2 Polyclonal antibody
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Uniprot No.：
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基因名：RAB3GAP2
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from internal of Human.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
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基因功能參考文獻：
- functionally severe RAB3GAP2 mutations cause Warburg Micro syndrome while hypomorphic RAB3GAP2 mutations can result in the milder Martsolf phenotype PMID: 20967465
- Data show that at chemical synapses, Rab3 performs specific functions in synpatic vesicle exocytosis. PMID: 18485483
- KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator RAB3GAP2 occurs in a GTP-dependent manner through MADD. PMID: 18849981
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相關疾?。?/div>Martsolf syndrome (MARTS); Warburg micro syndrome 2 (WARBM2)亞細胞定位：Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.蛋白家族：Rab3-GAP regulatory subunit family組織特異性：Ubiquitous.數據庫鏈接：
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