RAB39A Antibody

中文名稱：

RAB39A兔多克隆抗體
貨號：

CSB-PA614818LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of SH-SY5Y cells with CSB-PA614818LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RAB39A Polyclonal antibody
Uniprot No.：

Q14964
基因名：

RAB39A
別名：

rab related GTP binding protein antibody; Rab-39 antibody; Rab39 antibody; RAB39A antibody; RAB39A member RAS oncogene family antibody; Ras related protein Rab39A antibody; Ras-related protein Rab-39A antibody; RB39A_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ras-related protein Rab-39A protein (1-217AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RAB39A Antibody (CSB-PA614818LA01HU)，的標記方式是Non-conjugated。對于RAB39A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA614818LB01HU	RAB39A Antibody, HRP conjugated	ELISA
FITC	CSB-PA614818LC01HU	RAB39A Antibody, FITC conjugated
Biotin	CSB-PA614818LD01HU	RAB39A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation.
基因功能參考文獻：
1. Molecular pathways regulated by RAB39A are transcriptionally maintained by the formation of molecular complex with RXRB, NCOR and HDAC that also contribute to cancer stemness. PMID: 29648608
2. C9ORF72 causes suboptimal autophagy PMID: 27494456
3. our findings indicate that Rab39a favours chlamydial replication and infectivity. This is the first report showing that a late endocytic Rab GTPase is involved in chlamydial infection development. PMID: 26163492
4. Results show that Rab39a interacts with caspase-1 and suggest that Rab39a functions as a trafficking adaptor linking caspase-1 to IL-1beta secretion. PMID: 19833722
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
蛋白家族：

Small GTPase superfamily, Rab family
數據庫鏈接：

HGNC: 16521

KEGG: hsa:54734

STRING: 9606.ENSP00000322594

UniGene: Hs.354906

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