RAB39A Antibody

說明書

中文名稱：

RAB39A兔多克隆抗體
貨號：

CSB-PA040885
規格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA040885(RAB39A Antibody) at dilution 1/5, on the right is treated with synthetic peptide. (Original magnification: ×200)
其他：

產品詳情

Uniprot No.：

Q14964
基因名：

RAB39A
別名：

rab related GTP binding protein antibody; Rab-39 antibody; Rab39 antibody; RAB39A antibody; RAB39A member RAS oncogene family antibody; Ras related protein Rab39A antibody; Ras-related protein Rab-39A antibody; RB39A_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthetic peptide of Human RAB39A
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:5-1:20

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation.
基因功能參考文獻：
1. Molecular pathways regulated by RAB39A are transcriptionally maintained by the formation of molecular complex with RXRB, NCOR and HDAC that also contribute to cancer stemness. PMID: 29648608
2. C9ORF72 causes suboptimal autophagy PMID: 27494456
3. our findings indicate that Rab39a favours chlamydial replication and infectivity. This is the first report showing that a late endocytic Rab GTPase is involved in chlamydial infection development. PMID: 26163492
4. Results show that Rab39a interacts with caspase-1 and suggest that Rab39a functions as a trafficking adaptor linking caspase-1 to IL-1beta secretion. PMID: 19833722
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
蛋白家族：

Small GTPase superfamily, Rab family
數據庫鏈接：

HGNC: 16521

KEGG: hsa:54734

STRING: 9606.ENSP00000322594

UniGene: Hs.354906

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