RAB18 Antibody
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中文名稱：RAB18兔多克隆抗體
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貨號：CSB-PA981899
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981899(RAB18 Antibody) at dilution 1/300, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA981899(RAB18 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：AA959686 antibody; RAB18 antibody; RAB18 small GTPase antibody; RAB18; member RAS oncogene family antibody; RAB18_HUMAN antibody; RAB18LI1 antibody; Ras related protein Rab 18 antibody; Ras-asssociated protein RAB18 antibody; Ras-related protein Rab-18 antibody; RP11-148B2.1 antibody; WARBM3 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human RAB18
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:10000 WB 1:500-1:2000 IHC 1:200-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts. Plays a role in apical endocytosis/recycling. Plays a key role in eye and brain development and neurodegeneration.
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基因功能參考文獻：
- The authors found that the previously documented interaction between TRAPPII and COPI was also required for the recruitment of Rab18 to the lipid droplet. PMID: 28003315
- findings suggest that RAB18 rs3765133 polymorphism affects the development of specific brain regions, particularly the cerebellum, in healthy people. PMID: 24996981
- RAB18 is the direct target of miR-455-5p in gastric cancer. PMID: 27451075
- Warburg Micro syndrome is caused by RAB18 deficiency. PMID: 26063829
- These results suggest that Rab18 has an important role in viral assembly through the trafficking of the hepatitis C virus core protein to lipid droplets. PMID: 24997429
- High RAB18 expression is associated with glioma. PMID: 24477653
- Rab18-mediated membrane trafficking of FASN and NS3 facilitates dengue virus replication. PMID: 24696471
- Rab18 interacts with the HCV nonstructural protein NS5A. PMID: 23935497
- Hepatitis B virus X protein enhances proliferation of hepatoma cells through Rab18. PMID: 23471881
- Micro syndrome has been associated with causative mutations in three disease genes: RAB3GAP1, RAB3GAP2 and RAB18. Martsolf syndrome has been associated with a mutation in RAB3GAP2. [Review] PMID: 23176487
- performed autozygosity mapping in five consanguineous families with Warburg micro syndrome without RAB3GAP1/2 mutations and identified loss-of-function mutations in RAB18 PMID: 21473985
- Rab18 regulates lipid droplet-associated membrane formation PMID: 15914536
- analysis of a novel splice variant of human Rab18 gene PMID: 16147880
- Rab18 is reduced in pituitary tumors causing acromegaly and its overexpression reverts growth hormone hypersecretion. PMID: 18349058
- Rab18 and Rab43 have key roles in ER-Golgi trafficking. PMID: 18664496
- Rab18 is recruited to lipid droplets during lipolysis PMID: 16207721
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相關疾病：Warburg micro syndrome 3 (WARBM3)
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亞細胞定位：Apical cell membrane. Lipid droplet.
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蛋白家族：Small GTPase superfamily, Rab family
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組織特異性：Ubiquitous.
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數據庫鏈接：
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