Phospho-PFKFB2 (S483) Antibody
-
中文名稱：磷酸化-PFKFB2 (S483)兔多克隆抗體
-
貨號：CSB-PA000708
-
規格：￥1090
-
圖片：
-
Western Blot analysis of Hela cells using Phospho-PFK-2 car (S483) Polyclonal Antibody -
Western Blot analysis of PC3 cells using Phospho-PFK-2 car (S483) Polyclonal Antibody
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 2 antibody; 6-bisphosphatase antibody; 6-P2ase 2 antibody; 6-P2ASE heart-type isozyme antibody; 6PF 2 K/Fru 2 6 P2ASE heart type isozyme antibody; 6PF-2-K/Fru-2 antibody; 6PF-2-K/Fru-26-P2ase 2 antibody; 6PF-2-K/Fru-26-P2ase heart-type isozyme antibody; F262_HUMAN antibody; Fructose 2 6 bisphosphatase cardiac isozyme antibody; Fructose-2 antibody; PFK 2/FBPase 2 antibody; PFK/FBPase 2 antibody; PFKFB cardiac antibody; PFKFB2 antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Synthesized peptide derived from Human PFK-2 car around the phosphorylation site of S483.
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產品提供形式：Liquid
-
應用范圍：WB, IHC, ELISA
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Synthesis and degradation of fructose 2,6-bisphosphate.
-
基因功能參考文獻：
- UCA1/miR-182/PFKFB2 axis modulates chemokine CXCL14 secretion, glycolysis and invasion of glioma cells in glioblastoma-associated stromal cells . PMID: 29655792
- Crystal structure of human and cattle heart PFKFB2 and the inhibitory influence of citrate on substrate binding has been described. PMID: 27802586
- Variation in PFKFB2 appears to reduce PFKFB2 expression in adipose and kidney tissues, and thereby increase risk for adiposity and diabetic nephropathy. PMID: 25662186
- Highly expressed PFKFB2 protein is associated with hepatocellular carcinoma. PMID: 24568531
- bifunctionality of PFK-2/FBPase-2 complements the metabolic zonation of the liver by ensuring coherent switching in response to insulin and glucagon. PMID: 24634222
- amino acids stimulate Fru-2,6-P2 synthesis by Akt-dependent PFKFB2 phosphorylation and activation and show how signaling and metabolism are inextricably linked. PMID: 23457334
- A persistent increase in 6-phosphofructo-2-kinase produced by a change in PFK-2/FBPase-2 isoform expression that may play an important role in the regulation of muscle glycolysis. PMID: 22241065
- Suggest that PFKFB2 is not an essential upstream regulator of the anti-leukemic effects of glucocorticoids. PMID: 21092265
- induction of de novo lipid synthesis by androgen requires transcriptional up-regulation of HK2 and PFKFB2, and phosphorylation of PFKFB2 generated by the PI3K/Akt signal pathway to supply the source for lipogenesis from glucose in prostate cancer cells. PMID: 20958264
- Human islets expressed the PFKFB2 and PFKFB3 isoforms. PFK-2/FBPase-2 protein rather than its product fructose 2,6-P(2) is the over-riding determinant of glucose-induced insulin secretion through regulation of glucokinase activity PMID: 18039179
顯示更多
收起更多
-
蛋白家族：Phosphoglycerate mutase family
-
組織特異性：Heart.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
