PSAT1 Antibody, HRP conjugated
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中文名稱：PSAT1兔多克隆抗體, HRP偶聯
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貨號：CSB-PA018838LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PSAT1 Polyclonal antibody
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Uniprot No.：
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基因名：PSAT1
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別名：EC 2.6.1.52 antibody; Endometrial progesterone induced protein antibody; EPIP antibody; MGC1460 antibody; NLS2 antibody; Phosphohydroxythreonine aminotransferase antibody; phosphoserine aminotransferase 1 antibody; Phosphoserine aminotransferase antibody; PSA antibody; PSAT antibody; Psat1 antibody; PSATD antibody; SERC_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Phosphoserine aminotransferase protein (104-206AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
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基因功能參考文獻：
- PSAT1 protein and mRNA levels were significantly associated to poor outcome to tamoxifen treatment of breast cancer. PMID: 28522855
- PSAT1, which is overexpressed in ER-negative breast cancers, is activated by ATF4 and promotes cell cycle progression via regulation of the GSK3beta/beta-catenin/cyclin D1 pathway. PMID: 29216929
- Data suggest that phosphoserine aminotransferase 1 (PSAT1) may be a promising anticancer therapeutic target. . PMID: 27372650
- High expression of PSAT is associated with Colon Cancer. PMID: 26439504
- PSAT1 expression positively correlates with the levels of phosphorylated cyclin D1 in non-small cell lung cancer. PMID: 25142862
- phosphoserine aminotransferase deficiency is associated with Neu-Laxova syndrome. PMID: 25152457
- we propose an idea that PSAT1 may be implicated in altered serine metabolism and schizophrenia spectrum conditions. PMID: 20955740
- nucleotide sequence and enzymatic activity of two isoforms generated by alternative splicing; differential expression depending upon tissue specificity and cellular proliferation status PMID: 12633500
- Overexpression of phosphoserine aminotransferase is associated with colorectal cancer development PMID: 18221502
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相關疾病：Phosphoserine aminotransferase deficiency (PSATD); Neu-Laxova syndrome 2 (NLS2)
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蛋白家族：Class-V pyridoxal-phosphate-dependent aminotransferase family, SerC subfamily
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組織特異性：Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
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數據庫鏈接：
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