PNCK Antibody
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中文名稱:PNCK兔多克隆抗體
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貨號:CSB-PA436748
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規格:¥2024
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圖片:
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其他:
產品詳情
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產品名稱:Rabbit anti-Homo sapiens (Human) PNCK Polyclonal antibody
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Uniprot No.:
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基因名:PNCK
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宿主:Rabbit
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反應種屬:Human,Mouse,Rat
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免疫原:Synthesized peptide derived from internal of Human CaMK1-β.
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免疫原種屬:Homo sapiens (Human)
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克隆類型:Polyclonal
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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產品提供形式:Liquid
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應用范圍:ELISA,WB,IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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功能:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.
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基因功能參考文獻:
- Pnck may be a marker of Trastuzumab resistance and possibly a therapeutic target in breast cancer. PMID: 25773930
- the relationship between PNCK and prognosis in clear cell renal cell carcinoma PMID: 23634203
- Pnck induces epidermal growth factor receptor degradation, most likely through perturbation of Hsp90 chaperone activity due to Hsp90 phosphorylation. Epidermal growth factor receptor degradation is coupled to proteasomal degradation of Pnck. PMID: 21325639
- Pnck induces ligand-independent EGFR degradation, and it may represent an attractive therapeutic target in EGFR-regulated oncogenesis. PMID: 18562482
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亞細胞定位:Cytoplasm. Nucleus.
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蛋白家族:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
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數據庫鏈接:
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