PKIB Antibody, FITC conjugated
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中文名稱：PKIB兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA883651LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) PKIB Polyclonal antibody
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Uniprot No.：
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基因名：PKIB
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別名：cAMP dependent protein kinase inhibitor 2 antibody; cAMP-dependent protein kinase inhibitor beta antibody; FLJ23817 antibody; IPKB_HUMAN antibody; OTTHUMP00000017115 antibody; OTTHUMP00000017116 antibody; OTTHUMP00000017117 antibody; PKI-beta antibody; PKIB antibody; PRKACN2 antibody; Protein kinase (cAMP dependent, catalytic) inhibitor beta antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human cAMP-dependent protein kinase inhibitor beta protein (1-77AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
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基因功能參考文獻(xiàn)：
- results indicate that PKIB promotes cell proliferation and tumorigenesis by activating the PI3K/Akt pathway in non-small cell lung cancer (NSCLC), implying that this is an important underlying mechanism that affects the progression of NSCLC PMID: 27325557
- mutation of the pseudosubstrate domain abolished the inhibitory activity of PKIB on protein kinase A activity, but had no effect on the interaction with GPR39, cell protection and induction of SRE-dependent transcription PMID: 24869658
- PKIB overexpression was strongly correlated with pAkt expression and triple-negative breast cancer, suggesting that PKIB overexpression might contribute to the tumor behavior and development of breast cancers. PMID: 23224602
- human PKIbeta gene (clone 436F11, GenBank with accession number: AF225513) was over-expressed in normal brain tissues PMID: 12061725
- PKIbeta may be a novel full-length gene related to human glioma and may provide a new way to gene therapy of glioma. PMID: 19035091
- Functional studies of the rat homolog PMID: 2052616
- Functional studies of the mouse homolog PMID: 7684369
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蛋白家族：PKI family
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數(shù)據(jù)庫鏈接：
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