NTAN1 Antibody, FITC conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) NTAN1 Polyclonal antibody
Uniprot No.：

Q96AB6
基因名：

NTAN1
別名：

NTAN1 antibody; Protein N-terminal asparagine amidohydrolase antibody; EC 3.5.1.121 antibody; Protein NH2-terminal asparagine amidohydrolase antibody; PNAA antibody; Protein NH2-terminal asparagine deamidase antibody; PNAD antibody; Protein N-terminal Asn amidase antibody; Protein N-terminal asparagine amidase antibody; Protein NTN-amidase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Protein N-terminal asparagine amidohydrolase protein (219-310AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn.
基因功能參考文獻(xiàn)：
1. Results indicate that hNTAN1 is highly selective for the hydrolysis of N-terminal peptidyl L-Asn. PMID: 21375249
亞細(xì)胞定位：

Cytoplasm.
數(shù)據(jù)庫鏈接：

HGNC: 29909

OMIM: 615367

KEGG: hsa:123803

STRING: 9606.ENSP00000287706

UniGene: Hs.592045

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