NDUFV2 Antibody
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中文名稱：NDUFV2兔多克隆抗體
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貨號：CSB-PA998153
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規格：￥1100
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圖片：
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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Jurkat cells, Raji cells, A431 cells, mouse skeletal muscle tissue, NIH/3T3 cells, Primary antibody: CSB-PA998153(NDUFV2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：24kDa subunit of Complex I antibody; CI-24k antibody; complex I 24kDa subunit antibody; complex I, mitochondrial respiratory 2 antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2 antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2 antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial antibody; NADH ubiquinone oxidoreductase 24 kDa subunit antibody; NADH-ubiquinone oxidoreductase 24 kDa subunit antibody; NADH-ubiquinone oxidoreductase flavoprotein 2 antibody; NDUFV2 antibody; NDUV2_HUMAN antibody; nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit antibody; Ubiquinoneflavoprotein 2 antibody; Ubiquinoneflavoprotein 2, mitochondrial precursor antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Fusion protein of Human NDUFV2
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
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基因功能參考文獻：
- haplotype T-C consisting of rs12457810 and rs12964485 in the 5'-upstream region of NDUFV2 may be a protective factor for the development of MDD in Han Chinese PMID: 26544616
- We have identified NDUFV2 mutations in two families with Complex I deficiency, including a novel mutation. PMID: 26008862
- The results show mitochondrial haplotypes associated with polymorphism of this gene are associated with elite middle and sprint power endurance in Japanese athletes PMID: 20551160
- There is no statistical significance between NDUFV2 gene promoter variants and susceptibility to schizophrenia in Han Chinese. PMID: 21190551
- The mitochondrial targeting sequence of NDUFV2 is located at the N-terminus of the precursor protein. Impairment of mitochondrial localization of NDUFV2 as a mechanistic basis for early-onset hypertrophic cardiomyopathy and encephalopathy was established. PMID: 21548921
- Three single nucleotide polymorphisms in the NDUFV2 gene, were studies in bipolar disorder pateints and controls. PMID: 20978456
- Our findings suggest further studies addressing the role of NDUFV2 variation in Parkinson's disease may be warranted. PMID: 20971673
- mutation causes early onset hypertrophic cardiomyopathy and encephalopathy PMID: 12754703
- Polymorphisms of this gene may be one of the genetic risk factors for bipolar disorder. PMID: 12815743
- Polymorphisms in the promoter region of NDUFV2 are a genetic risk factor for bipolar disorder. The association of the haplotypes -602G> A and -3542G> A polymorphisms with bipolar disorder was seen both in Japanese case-control samples and NIMH trios. PMID: 15450783
- NDUFV2 individual genotypes were not associated with schizophrenia, but the haplotype consisting of the two single nucleotide polymorphisms were significantly associated with schizophrenia. PMID: 16508936
- genetic variants of NDUFV2 may increase risk for bipolar disorder. PMID: 18199248
- This study found that the expressions of NDUFV2 were up-regulated in those from patients with Japanese bipolar II disorder and the mRNA levels of this gene were down-regulated in Caucasian schizophrenia. PMID: 19135101
- Data show that the haplotype consisting of rs6506640 (-342G > A) and rs906807 (86C > T) on the mitochondrial gene NDUFV2 is found to be associated with bipolar disorder. PMID: 19194776
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亞細胞定位：Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
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蛋白家族：Complex I 24 kDa subunit family
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數據庫鏈接：
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