NDUFAF1 Antibody
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中文名稱：NDUFAF1兔多克隆抗體
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貨號：CSB-PA226934
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規格：￥1100
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圖片：
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA226934(NDUFAF1 Antibody) at dilution 1/25. (Original magnification: ×200) -
The image is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA226934(NDUFAF1 Antibody) at dilution 1/25. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：CGI 65 antibody; CGI65 antibody; CIA30 antibody; CIA30_HUMAN antibody; Complex I intermediate associated protein 30 antibody; Complex I intermediate associated protein 30 mitochondrial antibody; Complex I intermediate-associated protein 30; mitochondrial antibody; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 1 antibody; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1 antibody; NADH:ubiquinone oxidoreductase complex assembly factor 1 antibody; NDUFAF 1 antibody; Ndufaf1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human NDUFAF1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Chaperone protein involved in early stages of the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
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基因功能參考文獻：
- a case of leukodystrophy associated with mitochondrial complex I deficiency due to a novel mutation in the NDUFAF1 gene. PMID: 24963768
- oncogenic K-Ras is able to induce significant alterations in mitochondrial protein expression, and identified NDUFAF1 as an important molecule whose low expression contributes to mitochondrial dysfunction induced by K-Ras. PMID: 25714130
- NDUFAF1 is an important protein for the assembly/stability of complex I (NADH:ubiquinone oxidoreductase). PMID: 16218961
- Study shows a mitochondrial function for Ecsit in the assembly of mitochondrial complex I, an N-terminal targeting signal directs Ecsit to mitochondria, where it interacts with assembly chaperone NDUFAF1. PMID: 17344420
- the involvement of NDUFAF1 in the assembly process could be indirect rather than direct via the binding to assembly intermediates PMID: 17383918
- CIA30 is a crucial component in the early assembly of complex I and mutations in its gene can cause mitochondrial disease PMID: 17557076
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亞細胞定位：Mitochondrion. Mitochondrion matrix.
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蛋白家族：CIA30 family
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組織特異性：Ubiquitous.
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數據庫鏈接：
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